渗透给药系统改良释放剂型的研究

Dudhat K
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引用次数: 0

摘要

渗透给药是一种控制药物长期释放的技术。在基于渗透原理的系统中,使用半透膜将两个隔间隔开,其中一个隔间含有药物,另一个隔间含有渗透剂。由于渗透剂将体内的水吸进药物室时产生的压力差,药物以受控的速度通过膜。该系统可以在很长一段时间内分散药物,从几个小时到几个月不等。渗透给药在许多方面优于传统的给药技术,包括患者依从性、不良反应和疗效
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An Insight to Modified Release Dosage Form with Osmotic Drug Delivery System
Osmotic drug delivery is a technique for managing the controlled, prolonged release of medications. A semi-permeable membrane is used to separate two compartments, one of which contains the medicine and the other of which contains an osmotic agent, in the system, which is based on the osmosis principle. The medicine is pushed through the membrane at a controlled rate thanks to the pressure differential created when the osmotic agent sucks water from the body into the drug compartment. The system can be set up to disperse medications over long periods of time, from a few hours to several months. Osmotic drug delivery is superior to conventional drug delivery techniques in a number of ways, including patient compliance, adverse effects, and efficacy
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