缓释羟考酮/纳洛酮治疗慢性疼痛

Future Prescriber Pub Date : 2009-02-26 DOI:10.1002/fps.43

Nicola O'Connell, Karen H Simpson FRCA, FFPMRCA

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Prolonged-release oxycodone/naloxone for chronic pain

Chronic pain is common, and opioid therapy is often required for pain management. Unfortunately, opioid-induced bowel dysfunction (OIBD) is a frequent and debilitating side-effect of opioid use. A new prolonged-release (PR) preparation of oxycodone/naloxone has been developed for moderate-to-severe pain that reduces OIBD in patients. In this article, we consider the mode of action and efficacy of this combination opioid therapy for chronic pain. Copyright © 2009 John Wiley & Sons, Ltd.

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Future Prescriber

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