使用贝叶斯时间序列模型评估联邦政策:估计医院再入院减少计划的因果影响。

IF 1.6 Q3 HEALTH CARE SCIENCES & SERVICES
Georgia Papadogeorgou, Fiammetta Menchetti, Christine Choirat, Jason H Wasfy, Corwin M Zigler, Fabrizia Mealli
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引用次数: 0

摘要

研究人员经常面临评估政策或计划的效果,这些政策或计划在一个时间点同时在整个单位人口中启动,其对目标人口的影响可能在之后的任何时期显现出来。在有随时间测量的数据的情况下,贝叶斯时间序列模型被用来估算政策启动后会发生什么,如果政策没有发生,为了估计因果效应。然而,关于目标估计的定义、基本假设、这些假设的合理性以及适当模型的选择的考虑还没有得到彻底的调查。在本文中,我们为大规模政策的评估建立了有用的估计。我们讨论了缺失潜在结果的估算依赖于一个假设,即使不可测试,也可以使用观察到的数据部分评估。我们举例说明了一种方法来评估这一关键的因果假设,并根据政策启动前的时间间隔的数据和使用经典的统计技术促进模型的推导。为了说明这一点,我们研究了医院再入院减少计划(HRRP),这是一项美国联邦干预措施,旨在改善入院的肺炎、急性心肌梗死或充血性心力衰竭患者的健康结果。我们评估了HRRP对美国和四个地理分区的老年人死亡率的影响,并在不同的时间窗口。我们发现,HRRP至少在一个地理区域和时间范围内增加了肺炎和急性心肌梗死的死亡率,并可能对公众健康产生有害影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluating Federal Policies Using Bayesian Time Series Models: Estimating the Causal Impact of the Hospital Readmissions Reduction Program.

Researchers are often faced with evaluating the effect of a policy or program that was simultaneously initiated across an entire population of units at a single point in time, and its effects over the targeted population can manifest at any time period afterwards. In the presence of data measured over time, Bayesian time series models have been used to impute what would have happened after the policy was initiated, had the policy not taken place, in order to estimate causal effects. However, the considerations regarding the definition of the target estimands, the underlying assumptions, the plausibility of such assumptions, and the choice of an appropriate model have not been thoroughly investigated. In this paper, we establish useful estimands for the evaluation of large-scale policies. We discuss that imputation of missing potential outcomes relies on an assumption which, even though untestable, can be partially evaluated using observed data. We illustrate an approach to evaluate this key causal assumption and facilitate model elicitation based on data from the time interval before policy initiation and using classic statistical techniques. As an illustration, we study the Hospital Readmissions Reduction Program (HRRP), a US federal intervention aiming to improve health outcomes for patients with pneumonia, acute myocardial infraction, or congestive failure admitted to a hospital. We evaluate the effect of the HRRP on population mortality among the elderly across the US and in four geographic subregions, and at different time windows. We find that the HRRP increased mortality from pneumonia and acute myocardial infraction across at least one geographical region and time horizon, and is likely to have had a detrimental effect on public health.

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来源期刊
Health Services and Outcomes Research Methodology
Health Services and Outcomes Research Methodology HEALTH CARE SCIENCES & SERVICES-
CiteScore
3.40
自引率
6.70%
发文量
28
期刊介绍: The journal reflects the multidisciplinary nature of the field of health services and outcomes research. It addresses the needs of multiple, interlocking communities, including methodologists in statistics, econometrics, social and behavioral sciences; designers and analysts of health policy and health services research projects; and health care providers and policy makers who need to properly understand and evaluate the results of published research. The journal strives to enhance the level of methodologic rigor in health services and outcomes research and contributes to the development of methodologic standards in the field. In pursuing its main objective, the journal also provides a meeting ground for researchers from a number of traditional disciplines and fosters the development of new quantitative, qualitative, and mixed methods by statisticians, econometricians, health services researchers, and methodologists in other fields. Health Services and Outcomes Research Methodology publishes: Research papers on quantitative, qualitative, and mixed methods; Case Studies describing applications of quantitative and qualitative methodology in health services and outcomes research; Review Articles synthesizing and popularizing methodologic developments; Tutorials; Articles on computational issues and software reviews; Book reviews; and Notices. Special issues will be devoted to papers presented at important workshops and conferences.
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