全动脉血运重建非泵送冠状动脉旁路移植术对左心室功能受损的影响

I. Moursi, K. Al Fakharany
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引用次数: 1

摘要

背景:动脉移植物具有耐久性的优点,并且可能通过减少移植物血管中原生冠状动脉疾病(CAD)的进展而具有保护作用。本研究旨在评价全动脉血运重建无泵冠状动脉旁路移植术(CABG)对射血分数(EF)≤35%的左室功能受损患者的短期疗效影响。方法对2006年8月至2015年8月在埃及Zagazig大学医院心胸外科行心肌血运重建术的1950例患者中EF≤35%的287例患者进行前瞻性登记研究。1组137例行全动脉离泵重建术(TAROP), 2组150例行常规技术(C-CABG)。结果1组住院死亡率较低,分别为4.37%和4.66%。组1患者重症监护时间和住院时间较短,差异有统计学意义。1组(TAROP) 113例(82.5%)和2组(C-CABG,利用乳腺内静脉移植物)113例(75.3%)患者1个月平均移植物通畅率分别为98.2%和80.5%。短期结果显示,术后平均LVEF显著改善,从29%±1.7%降至41.0%±2.0% (p <0.05),两组患者的NYHA分级均有改善。结论全动脉血运重建术在左心功能受损患者中的应用效果良好,并发症少,死亡率低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The impact of total arterial revascularization off pump coronary bypass grafting in impaired left ventricular function

Background

The Arterial grafts have the advantage of durability and may have a protective effect by reducing the progression of native coronary artery disease (CAD) in grafted vessels. This study aimed to evaluate the impact of total arterial revascularization off pump coronary artery bypass grafting (CABG) in impaired left ventricular (LV) function patients with Ejection Fraction (EF) ≤ 35% concerning the short-term results.

Methods

From August 2006 to August 2015, 287 patients with EF ≤ 35% out of 1950 patients underwent CABG in our Department of Cardiac-Thoracic Surgery, Zagazig University hospital, Egypt, for myocardial revascularization procedures were studied with a prospective registry of their data. Group 1 included 137 patients subjected to total arterial revascularization off Pump (TAROP) and Group 2 included 150 patients subjected to conventional technique (C-CABG).

Results

Hospital mortality was less in group 1 (4.37% versus 4.66%). The duration of intensive care unit stay and the hospital stay were shorter in the group 1, with statistical significance. The mean graft patency rate for 113 (82.5%) patients of group 1 (TAROP) and 113 (75.3%) group 2 (C-CABG, utilizing internal mammary and venous grafts) at one month were 98.2% and 80.5% respectively. The short-term outcome revealed that the mean postoperative LVEF improved significantly, from 29% ± 1.7% to 41.0% ± 2.0% (p < 0.05) for group 1 with an improvement of the NYHA classification of the patients in both groups.

Conclusions

Total arterial revascularization off-pump CABG in impaired left ventricular function can be achieved in most cases with low complication and mortality rates and accepted results.

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