{"title":"妊娠后期维生素D水平、甲状腺功能和产妇抑郁","authors":"M. Dabbaghmanesh, F. Vaziri, F. Najib, S. Nasiri","doi":"10.5812/WHB.68256","DOIUrl":null,"url":null,"abstract":"Background: Based on a possible association between thyroid function or serum 25-hydroxyvitamin D concentration and perinatal psychological symptoms, this study examined the potential link between antenatal depression and thyroid function or vitamin D level in the population of Shiraz city. Methods: This cross-sectional study was conducted on mothers, who were under prenatal care at a teaching hospital in Shiraz, during year 2015. Evaluation of depression was performed by the Edinburgh postnatal depression scale (EPDS). Eligible pregnant females aged ≥ 18 and at 26 to 28 weeks of gestation were passed to the laboratory to offer a blood sample to determine serum 25-hydroxyvitamin D, TSH, FT4, and TPOAb. Finally, data from 184 pregnant females was analyzed. Results: The mean depression score was 9.19 ± 4.44, with a median value of 9.50, and mode value of 13. Overall, 52 mothers (28.3%) had depression (depression score > 12). The mothers with and without depression were not different in relation to 25hydroxyvitamin D, TSH, FT4, and TPOAb levels. No association was established between thyroid function and antenatal depression with a binary logistic regression analysis. Also, vitamin D deficient mothers did not have more chance of being depressed. No correlation was detected between thyroid function and vitamin D levels. Conclusions: Based on the current findings, no association was observed between antenatal depression and thyroid function or vitamin D deficiency.","PeriodicalId":52810,"journal":{"name":"Women''s Health Bulletin","volume":"11 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Vitamin D Level, Thyroid Function, and Maternal Depression in Late Pregnancy\",\"authors\":\"M. Dabbaghmanesh, F. Vaziri, F. Najib, S. Nasiri\",\"doi\":\"10.5812/WHB.68256\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Based on a possible association between thyroid function or serum 25-hydroxyvitamin D concentration and perinatal psychological symptoms, this study examined the potential link between antenatal depression and thyroid function or vitamin D level in the population of Shiraz city. Methods: This cross-sectional study was conducted on mothers, who were under prenatal care at a teaching hospital in Shiraz, during year 2015. Evaluation of depression was performed by the Edinburgh postnatal depression scale (EPDS). Eligible pregnant females aged ≥ 18 and at 26 to 28 weeks of gestation were passed to the laboratory to offer a blood sample to determine serum 25-hydroxyvitamin D, TSH, FT4, and TPOAb. Finally, data from 184 pregnant females was analyzed. Results: The mean depression score was 9.19 ± 4.44, with a median value of 9.50, and mode value of 13. Overall, 52 mothers (28.3%) had depression (depression score > 12). The mothers with and without depression were not different in relation to 25hydroxyvitamin D, TSH, FT4, and TPOAb levels. No association was established between thyroid function and antenatal depression with a binary logistic regression analysis. Also, vitamin D deficient mothers did not have more chance of being depressed. No correlation was detected between thyroid function and vitamin D levels. Conclusions: Based on the current findings, no association was observed between antenatal depression and thyroid function or vitamin D deficiency.\",\"PeriodicalId\":52810,\"journal\":{\"name\":\"Women''s Health Bulletin\",\"volume\":\"11 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-06-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Women''s Health Bulletin\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5812/WHB.68256\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Women''s Health Bulletin","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5812/WHB.68256","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Vitamin D Level, Thyroid Function, and Maternal Depression in Late Pregnancy
Background: Based on a possible association between thyroid function or serum 25-hydroxyvitamin D concentration and perinatal psychological symptoms, this study examined the potential link between antenatal depression and thyroid function or vitamin D level in the population of Shiraz city. Methods: This cross-sectional study was conducted on mothers, who were under prenatal care at a teaching hospital in Shiraz, during year 2015. Evaluation of depression was performed by the Edinburgh postnatal depression scale (EPDS). Eligible pregnant females aged ≥ 18 and at 26 to 28 weeks of gestation were passed to the laboratory to offer a blood sample to determine serum 25-hydroxyvitamin D, TSH, FT4, and TPOAb. Finally, data from 184 pregnant females was analyzed. Results: The mean depression score was 9.19 ± 4.44, with a median value of 9.50, and mode value of 13. Overall, 52 mothers (28.3%) had depression (depression score > 12). The mothers with and without depression were not different in relation to 25hydroxyvitamin D, TSH, FT4, and TPOAb levels. No association was established between thyroid function and antenatal depression with a binary logistic regression analysis. Also, vitamin D deficient mothers did not have more chance of being depressed. No correlation was detected between thyroid function and vitamin D levels. Conclusions: Based on the current findings, no association was observed between antenatal depression and thyroid function or vitamin D deficiency.