聚合酶链式反应(PCR)检测人乳头瘤病毒基因型在尖锐湿疣女性中的流行

IF 0.4 Q4 ONCOLOGY
M. Ghobadi, Haniyeh Bashi Zadeh Fakhar, Babak Shaghaghi
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引用次数: 0

摘要

背景:人乳头瘤病毒(HPV)的基因型分布需要详细确定,因为它是一个重要的问题,当涉及到公共卫生和准备疫苗,因为不同地区的HPV类型可能不同。目的:本研究旨在报告伊朗北部萨里妇女中HPV类型的频率。方法:2018年10月至2019年4月,对妇科医生对50例尖锐湿疣妇女阴道和宫颈分泌物进行无菌拭子检测,采用聚合酶链反应(PCR)检测HPV基因分型的流行情况。结果:50例尖锐湿疣患者阴道拭子样本中,尖锐湿疣女性HPV类型的频率分布包括5例(10.0%),2种高危血清型,同时血清型为4%(16,18)、4%(18,35)、2%(66,67)、1例(2%)HPV 33、1例(2%)HPV 34、1例(2%)HPV 35、2例(4%)HPV 66、1例(2%)HPV 67、1例(2%)HPV 68。结论:由于HPV基因型在不同地区存在差异,这些结果可用于筛查、管理和针对Sari常见病毒类型的目标人群接种疫苗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Prevalence of Human Papillomavirus Genotypes in Women with Genital Warts Using Polymerase Chain Reaction (PCR)
Background: The genotypic distribution of human papillomavirus (HPV) needs to be determined with detail as it is an important issue when it comes to public health and preparing vaccines since the HPV type may be different in various areas. Objectives: This study aimed at reporting the frequency of HPV types among women in Sari in the north of Iran. Methods: From 2018 October to 2019 April, 50 sterile swabs of vaginal and cervical discharge of women with genital warts, which were performed by a gynecologist, were examined to determine the prevalence of HPV genotyping by using polymerase chain reaction (PCR). Results: From 50 vaginal swab samples of patients with genital warts, the frequency distribution of types of HPV in women with genital warts included 5 patients (10.0%) with 2 high-risk serotypes as simultaneous serotypes 4% (16, 18), 4% (18, 35), 2% (66, 67), 1 patient (2%) HPV 33, 1 patient (2%) HPV 34, 1 patient (2%) 1 patient (2%) HPV 35, 2 patients (4%) HPV 66, 1 patient (2%) HPV 67, and 1 patient (2%) HPV 68. Conclusions: Since HPV genotype varies in diverse areas, these results can be used for screening, management, and vaccination of the target population against the common types of virus in Sari.
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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
67
期刊介绍: International Journal of Cancer Management (IJCM) publishes peer-reviewed original studies and reviews on cancer etiology, epidemiology and risk factors, novel approach to cancer management including prevention, diagnosis, surgery, radiotherapy, medical oncology, and issues regarding cancer survivorship and palliative care. The scope spans the spectrum of cancer research from the laboratory to the clinic, with special emphasis on translational cancer research that bridge the laboratory and clinic. We also consider original case reports that expand clinical cancer knowledge and convey important best practice messages.
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