一项横断面研究评估导致哮喘失控的因素

M. Meena, G. Rajawat, P. Arora, S. Koolwal, Hemant Sakkarwal, A. Singh
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引用次数: 0

摘要

简介:哮喘是一种异质性疾病,通常以慢性气道炎症为特征。各种诱因,缺乏对疾病的了解,以及对正确吸入技术的不了解导致疾病控制不良。本研究旨在通过哮喘控制试验(ACT)研究导致哮喘失控的因素,并探索改善哮喘控制的其他途径。材料和方法:根据全球哮喘倡议(GINA)指南,180例诊断为支气管哮喘的患者,>18岁,在门诊环境中入组研究。使用自我给药ACT评估哮喘控制水平。使用基于GINA指南的问卷评估导致哮喘失控的因素。结果:我们的研究发现,大多数患者(66.11%)哮喘控制不良,其次是控制良好(24.44%)。哮喘得到完全控制的患者仅为9.44%。受试者ACT得分的平均值为17.5±4.16,中位数(25 - 75百分位)为17(15-20),范围为7-25。吸烟(P < 0.0001)、哮喘教育程度低(P < 0.0001)、使用吸入器的社会污名化(P < 0.0001)、错误的吸入技术(P < 0.0001)、环境触发因素(P < 0.0001)、相关合共病(P = 0.005)、治疗依从性差(P < 0.0001)、治疗不当(P < 0.0001)和频繁住院(P = 0.006)是导致哮喘未得到控制的因素。结论:本研究确定了在门诊临床环境中导致哮喘高患病率的各种因素。综合评估导致哮喘控制不良的常见危险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A cross-sectional study to evaluate factors responsible for uncontrolled asthma
INTRODUCTION: Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation. Various triggers, lack of knowledge about the disease, and unawareness about the correct inhalation techniques lead to poor control of the disease. This study aimed to study the factors responsible for uncontrolled asthma using the asthma control test (ACT) and explore other ways to improve asthma control. MATERIALS AND METHODS: One hundred and eighty diagnosed cases of bronchial asthma according to Global Initiative for Asthma (GINA) guidelines, >18 years were enrolled for the study in an outpatient setting. The level of asthma control was assessed using the self-administered ACT. Factors responsible for uncontrolled asthma were evaluated using a questionnaire based on GINA guidelines. RESULTS: Our study noted that in the majority (66.11%) of patients, asthma was poorly controlled followed by well-controlled (24.44%). Asthma was perfectly controlled in only 9.44% of patients. The mean value of the ACT score of study subjects was 17.5 ± 4.16 with a median (25th–75th percentile) of 17 (15–20) within the range of 7–25. Smoking (P < 0.0001), poor education about asthma (P < 0.0001), social stigma regarding inhaler use (P < 0.0001), wrong inhalation techniques (P < 0.0001), environmental triggers (P < 0.0001), associated comorbidities (P = 0.005), poor adherence to treatment (P < 0.0001), inappropriate therapy (P < 0.0001), and frequent hospitalizations (P = 0.006) were the factors responsible for uncontrolled asthma. CONCLUSION: The present study identified various factors responsible for the high prevalence of asthma in an outpatient clinical setting. Common risk factors that contribute to poor asthma control were assessed in a comprehensive manner.
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