E. Zonana-Farca , A. Sedano-Lozano , E.A. Ramirez-Perez , A. Zárate-Osorno , M. García-Sáenz , A. Lozano-Zalce
{"title":"前列腺癌治疗中的体外放射治疗:1993-2015年的个人经验","authors":"E. Zonana-Farca , A. Sedano-Lozano , E.A. Ramirez-Perez , A. Zárate-Osorno , M. García-Sáenz , A. Lozano-Zalce","doi":"10.1016/j.uromx.2016.05.006","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>In this work the changes in and evolution of radiotherapy for the treatment of prostate cancer in the last decades are described. This includes the application of advanced technology that incorporates imaging and computer systems into the new linear accelerators designed to apply high doses of radiation to the prostate, significantly diminishing the toxicity to the surrounding tissues.</p></div><div><h3>Aims</h3><p>Results found in the international literature are analyzed that consider increasing the radiation doses with the 3D-CRT and IMRT techniques, and in this manner improve biochemical failure-free survival and overall survival, especially in intermediate and high-risk patients with clinically localized prostate cancer, as well as adding radiotherapy and neoadjuvant, concomitant, and adjuvant hormone therapy.</p></div><div><h3>Materials and methods</h3><p>Presented herein is the personal experience that included 38 patients with clinically localized prostate cancer treated in private practice with external beam radiotherapy and hormone therapy as primary treatment, as well as the experience including 46 patients with pT3 disease after radical prostatectomy that received adjuvant treatments of radiotherapy and hormone therapy.</p></div><div><h3>Results</h3><p>Even though this clinical study includes a small number of patients, to the best of our knowledge it is the first and only report in the national literature on the use and benefits of the combined treatment of external beam radiotherapy and hormone therapy as primary treatment of clinically localized prostate cancer and as combined adjuvant treatment in patients with pT3 disease after radical prostatectomy.</p></div>","PeriodicalId":34909,"journal":{"name":"Revista mexicana de urologia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.uromx.2016.05.006","citationCount":"1","resultStr":"{\"title\":\"Radioterapia externa en el tratamiento del cáncer de la próstata: experiencia personal 1993-2015\",\"authors\":\"E. Zonana-Farca , A. Sedano-Lozano , E.A. Ramirez-Perez , A. Zárate-Osorno , M. García-Sáenz , A. Lozano-Zalce\",\"doi\":\"10.1016/j.uromx.2016.05.006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>In this work the changes in and evolution of radiotherapy for the treatment of prostate cancer in the last decades are described. This includes the application of advanced technology that incorporates imaging and computer systems into the new linear accelerators designed to apply high doses of radiation to the prostate, significantly diminishing the toxicity to the surrounding tissues.</p></div><div><h3>Aims</h3><p>Results found in the international literature are analyzed that consider increasing the radiation doses with the 3D-CRT and IMRT techniques, and in this manner improve biochemical failure-free survival and overall survival, especially in intermediate and high-risk patients with clinically localized prostate cancer, as well as adding radiotherapy and neoadjuvant, concomitant, and adjuvant hormone therapy.</p></div><div><h3>Materials and methods</h3><p>Presented herein is the personal experience that included 38 patients with clinically localized prostate cancer treated in private practice with external beam radiotherapy and hormone therapy as primary treatment, as well as the experience including 46 patients with pT3 disease after radical prostatectomy that received adjuvant treatments of radiotherapy and hormone therapy.</p></div><div><h3>Results</h3><p>Even though this clinical study includes a small number of patients, to the best of our knowledge it is the first and only report in the national literature on the use and benefits of the combined treatment of external beam radiotherapy and hormone therapy as primary treatment of clinically localized prostate cancer and as combined adjuvant treatment in patients with pT3 disease after radical prostatectomy.</p></div>\",\"PeriodicalId\":34909,\"journal\":{\"name\":\"Revista mexicana de urologia\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.uromx.2016.05.006\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista mexicana de urologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2007408516300234\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista mexicana de urologia","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2007408516300234","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Radioterapia externa en el tratamiento del cáncer de la próstata: experiencia personal 1993-2015
Background
In this work the changes in and evolution of radiotherapy for the treatment of prostate cancer in the last decades are described. This includes the application of advanced technology that incorporates imaging and computer systems into the new linear accelerators designed to apply high doses of radiation to the prostate, significantly diminishing the toxicity to the surrounding tissues.
Aims
Results found in the international literature are analyzed that consider increasing the radiation doses with the 3D-CRT and IMRT techniques, and in this manner improve biochemical failure-free survival and overall survival, especially in intermediate and high-risk patients with clinically localized prostate cancer, as well as adding radiotherapy and neoadjuvant, concomitant, and adjuvant hormone therapy.
Materials and methods
Presented herein is the personal experience that included 38 patients with clinically localized prostate cancer treated in private practice with external beam radiotherapy and hormone therapy as primary treatment, as well as the experience including 46 patients with pT3 disease after radical prostatectomy that received adjuvant treatments of radiotherapy and hormone therapy.
Results
Even though this clinical study includes a small number of patients, to the best of our knowledge it is the first and only report in the national literature on the use and benefits of the combined treatment of external beam radiotherapy and hormone therapy as primary treatment of clinically localized prostate cancer and as combined adjuvant treatment in patients with pT3 disease after radical prostatectomy.
期刊介绍:
Revista Mexicana de Urología (RMU) [Mexican Journal of Urology] (ISSN: 0185-4542 / ISSN electronic: 2007-4085) is bimonthly publication that disseminates research by academicians and professionals of the international medical community interested in urological subjects, in the format of original articles, clinical cases, review articles brief communications and letters to the editor. Owing to its nature, it is publication with international scope that disseminates contributions in Spanish and English that are rigorously reviewed by peers under the double blind modality. Neither journalistic documents nor those that lack rigorous medical or scientific support are suitable for publication.