{"title":"危重老年患者血清镁水平的影响——以某农村教学医院为例","authors":"Sunil Kumar MD, PGDGM , Shraddha Jain MS , Sachin Agrawal MD, PGDGM , Akshay Honmode MD","doi":"10.1016/j.jcgg.2016.04.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Background/Purpose</h3><p>Magnesium deficiency has been a common, but easily ignored, electrolyte abnormality. Studies on magnesium deficiency are lacking in India, especially in a rural setting. Here, we have correlated serum magnesium levels with outcomes in elderly patients admitted to the medical intensive care unit with respect to the length of intensive care unit stay, need for mechanical ventilatory support and its duration, and outcome (discharge/death).</p></div><div><h3>Methods</h3><p>A prospective, observational study was conducted in patients aged 60 years and older, who had been admitted to the intensive care unit of the medicine department for over a year. The chi-square test was applied to correlate hypomagnesemia with the outcome.</p></div><div><h3>Results</h3><p>In our study, 59.30% of the elderly patients had hypomagnesemia. Compared with patients with a normal magnesium level, hypomagnesemic patients had no correlation with the duration of medical intensive care unit stay (5.57<!--> <!-->±<!--> <!-->6.10 days vs. 5.61<!--> <!-->±<!--> <!-->5.55 days), but the need for mechanical ventilation (57.84% vs. 45.71%), rate of discharge from the intensive care unit or cure (60.28% vs. 71.42% ), rate of death (39.21% vs. 28.57%), and mean duration of ventilation (3.07<!--> <!-->±<!--> <!-->5.05 days vs. 2.15<!--> <!-->±<!--> <!-->3.46 days) were higher. However, no significant statistical difference was found between these groups.</p></div><div><h3>Conclusion</h3><p>Hypomagnesemia was associated with a slightly higher mortality rate. Requirement and duration of ventilatory support were also higher, although not statistically significant. Hypomagnesemia was not found to have any impact on the duration of medical intensive care unit stay. Monitoring of serum magnesium levels may have prognostic and perhaps therapeutic implications in the elderly.</p></div>","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"7 3","pages":"Pages 104-108"},"PeriodicalIF":0.0000,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jcgg.2016.04.002","citationCount":"14","resultStr":"{\"title\":\"Impact of serum magnesium levels in critically ill elderly patients—A study in a rural teaching hospital\",\"authors\":\"Sunil Kumar MD, PGDGM , Shraddha Jain MS , Sachin Agrawal MD, PGDGM , Akshay Honmode MD\",\"doi\":\"10.1016/j.jcgg.2016.04.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background/Purpose</h3><p>Magnesium deficiency has been a common, but easily ignored, electrolyte abnormality. Studies on magnesium deficiency are lacking in India, especially in a rural setting. Here, we have correlated serum magnesium levels with outcomes in elderly patients admitted to the medical intensive care unit with respect to the length of intensive care unit stay, need for mechanical ventilatory support and its duration, and outcome (discharge/death).</p></div><div><h3>Methods</h3><p>A prospective, observational study was conducted in patients aged 60 years and older, who had been admitted to the intensive care unit of the medicine department for over a year. The chi-square test was applied to correlate hypomagnesemia with the outcome.</p></div><div><h3>Results</h3><p>In our study, 59.30% of the elderly patients had hypomagnesemia. Compared with patients with a normal magnesium level, hypomagnesemic patients had no correlation with the duration of medical intensive care unit stay (5.57<!--> <!-->±<!--> <!-->6.10 days vs. 5.61<!--> <!-->±<!--> <!-->5.55 days), but the need for mechanical ventilation (57.84% vs. 45.71%), rate of discharge from the intensive care unit or cure (60.28% vs. 71.42% ), rate of death (39.21% vs. 28.57%), and mean duration of ventilation (3.07<!--> <!-->±<!--> <!-->5.05 days vs. 2.15<!--> <!-->±<!--> <!-->3.46 days) were higher. However, no significant statistical difference was found between these groups.</p></div><div><h3>Conclusion</h3><p>Hypomagnesemia was associated with a slightly higher mortality rate. Requirement and duration of ventilatory support were also higher, although not statistically significant. Hypomagnesemia was not found to have any impact on the duration of medical intensive care unit stay. Monitoring of serum magnesium levels may have prognostic and perhaps therapeutic implications in the elderly.</p></div>\",\"PeriodicalId\":100764,\"journal\":{\"name\":\"Journal of Clinical Gerontology and Geriatrics\",\"volume\":\"7 3\",\"pages\":\"Pages 104-108\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.jcgg.2016.04.002\",\"citationCount\":\"14\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Clinical Gerontology and Geriatrics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2210833516300429\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Gerontology and Geriatrics","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2210833516300429","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Impact of serum magnesium levels in critically ill elderly patients—A study in a rural teaching hospital
Background/Purpose
Magnesium deficiency has been a common, but easily ignored, electrolyte abnormality. Studies on magnesium deficiency are lacking in India, especially in a rural setting. Here, we have correlated serum magnesium levels with outcomes in elderly patients admitted to the medical intensive care unit with respect to the length of intensive care unit stay, need for mechanical ventilatory support and its duration, and outcome (discharge/death).
Methods
A prospective, observational study was conducted in patients aged 60 years and older, who had been admitted to the intensive care unit of the medicine department for over a year. The chi-square test was applied to correlate hypomagnesemia with the outcome.
Results
In our study, 59.30% of the elderly patients had hypomagnesemia. Compared with patients with a normal magnesium level, hypomagnesemic patients had no correlation with the duration of medical intensive care unit stay (5.57 ± 6.10 days vs. 5.61 ± 5.55 days), but the need for mechanical ventilation (57.84% vs. 45.71%), rate of discharge from the intensive care unit or cure (60.28% vs. 71.42% ), rate of death (39.21% vs. 28.57%), and mean duration of ventilation (3.07 ± 5.05 days vs. 2.15 ± 3.46 days) were higher. However, no significant statistical difference was found between these groups.
Conclusion
Hypomagnesemia was associated with a slightly higher mortality rate. Requirement and duration of ventilatory support were also higher, although not statistically significant. Hypomagnesemia was not found to have any impact on the duration of medical intensive care unit stay. Monitoring of serum magnesium levels may have prognostic and perhaps therapeutic implications in the elderly.