Comparación de la efectividad de 2 esquemas de preparación intestinal para colonoscopia en el Hospital General de México

Introduction

Colonoscopy is the “gold standard” for the detection of polyps and precancerous lesions. Adequate cleansing is essential for an effective colonoscopy. Intestinal preparations should be effective, safe and well tolerated by the patient.

Objetive

To compare the bowel cleansing efficacy, tolerability and cost of 2 colonic preparations: 4 l polyethylene glycol vs. 2 l polyethylene + 10 mg bisacodyl.

Material and Methods

A cross-sectional, prolective, comparative and analytical study was conducted including patients referred for colonoscopy due to any indication, aged between 18 and 85 years. We excluded patients with a history of allergy to the formulations used, heart failure and resection of a segment of the colon. Two groups were formed by simple randomisation: group 1 received the standard preparation of 4 litres of polyethylene glycol (PEG), and group 2 received 2 l PEG and 10 mg bisacodyl.

Results

The study included a total of 92 patients, of which 18 were ruled out. Out of the final 74 patients, 37 (50%) were male and 50% were female. Group 1 included 39 patients (53%) and group 2 included 35 patients (47%), and the mean age was 50 years. Tolerance to the preparation was measured using a Likert scale, with a mean result of 4 points in both groups. Efficacy was measured using a Boston scale, with a value of 7.36 in group 1 and of 7.43 in group 2 (RR 0.063).

Conclusions

The study found no significant differences in colon cleansing and tolerance between groups. The preparation containing bisacodyl was less expensive.