{"title":"来自安第斯山脉和厄瓜多尔太平洋沿岸地区的非洲后裔的遗传祖先","authors":"Germán Burgos , Verónica Gomes , Masinda Nguidi , Mariana Seguro , Alejandra Garzón-Salazar , Manuel Calvopiña , Dayana Aguilar , Grace Gamboa , Sonia Zapata , Alejandro Cabrera-Andrade , Rodrigo Flores-Espinoza , Filipa Simão , Angel Carracedo , Leonor Gusmão","doi":"10.1016/j.fsigss.2022.10.053","DOIUrl":null,"url":null,"abstract":"<div><p>This study aimed to investigate genetic diversity and ancestry in Afro-descendants from the Andes (AN) and the Pacific Coast (PC) regions of Ecuador, using autosomal and lineage markers. CR-mtDNA and PPY23-STRs showed high haplotype diversities. Statistically significant differences were found between AN and PC. Due to different patterns of sex-biased matting, differences between regions were more pronounced for the mtDNA than for the Y-chromosomal markers. A lower African ancestry was detected in AN than PC, for autosomal and both maternal and paternal lineage markers.</p></div>","PeriodicalId":56262,"journal":{"name":"Forensic Science International: Genetics Supplement Series","volume":"8 ","pages":"Pages 254-256"},"PeriodicalIF":0.5000,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1875176822000890/pdfft?md5=24fe1984e11e39a463b538e0d0e05284&pid=1-s2.0-S1875176822000890-main.pdf","citationCount":"1","resultStr":"{\"title\":\"Genetic ancestry in Afro-descendants from the Andes and Pacific Coast regions of Ecuador\",\"authors\":\"Germán Burgos , Verónica Gomes , Masinda Nguidi , Mariana Seguro , Alejandra Garzón-Salazar , Manuel Calvopiña , Dayana Aguilar , Grace Gamboa , Sonia Zapata , Alejandro Cabrera-Andrade , Rodrigo Flores-Espinoza , Filipa Simão , Angel Carracedo , Leonor Gusmão\",\"doi\":\"10.1016/j.fsigss.2022.10.053\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>This study aimed to investigate genetic diversity and ancestry in Afro-descendants from the Andes (AN) and the Pacific Coast (PC) regions of Ecuador, using autosomal and lineage markers. CR-mtDNA and PPY23-STRs showed high haplotype diversities. Statistically significant differences were found between AN and PC. Due to different patterns of sex-biased matting, differences between regions were more pronounced for the mtDNA than for the Y-chromosomal markers. A lower African ancestry was detected in AN than PC, for autosomal and both maternal and paternal lineage markers.</p></div>\",\"PeriodicalId\":56262,\"journal\":{\"name\":\"Forensic Science International: Genetics Supplement Series\",\"volume\":\"8 \",\"pages\":\"Pages 254-256\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2022-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S1875176822000890/pdfft?md5=24fe1984e11e39a463b538e0d0e05284&pid=1-s2.0-S1875176822000890-main.pdf\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Forensic Science International: Genetics Supplement Series\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1875176822000890\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"GENETICS & HEREDITY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Forensic Science International: Genetics Supplement Series","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1875176822000890","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"GENETICS & HEREDITY","Score":null,"Total":0}
Genetic ancestry in Afro-descendants from the Andes and Pacific Coast regions of Ecuador
This study aimed to investigate genetic diversity and ancestry in Afro-descendants from the Andes (AN) and the Pacific Coast (PC) regions of Ecuador, using autosomal and lineage markers. CR-mtDNA and PPY23-STRs showed high haplotype diversities. Statistically significant differences were found between AN and PC. Due to different patterns of sex-biased matting, differences between regions were more pronounced for the mtDNA than for the Y-chromosomal markers. A lower African ancestry was detected in AN than PC, for autosomal and both maternal and paternal lineage markers.
期刊介绍:
The Journal of Forensic Science International Genetics Supplement Series is the perfect publication vehicle for the proceedings of a scientific symposium, commissioned thematic issues, or for disseminating a selection of invited articles. The Forensic Science International Genetics Supplement Series is part of a duo of publications on forensic genetics, published by Elsevier on behalf of the International Society for Forensic Genetics.