在器官组织鉴定mRNA测定中增加脂肪标记物

IF 0.5 Q4 GENETICS & HEREDITY

Forensic Science International: Genetics Supplement Series Pub Date : 2022-12-01 DOI:10.1016/j.fsigss.2022.09.012

Margreet van den Berge, Titia Sijen

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引用次数: 0

摘要

在荷兰法医研究所，在个案工作中经常要求对用于器官组织鉴定的信使核糖核酸进行分析。以前版本的检测（表示为Organtyper）缺乏识别脂肪组织的标志物，而这在个案工作中偶尔会受到质疑。在这里，在将三种潜在的脂肪标志物纳入最终的Organtyper测定之前，对其进行了检查。从个案研究的结果来看，脂肪标志物的附加值变得清晰起来。

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Addition of an adipose marker to the organ tissue identification mRNA assay

At the Netherlands Forensic Institute, mRNA profiling for the purpose of organ tissue identification is frequently requested in casework. The previous version of the assay (denoted Organtyper) lacked markers for identifying adipose tissue, while this was occasionally questioned in casework. Here, three potential adipose markers are examined before incorporating one into the final Organtyper assay. The added value of the adipose marker becomes clear from looking at casework results.

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来源期刊

Forensic Science International: Genetics Supplement Series Medicine-Pathology and Forensic Medicine

CiteScore

0.40

自引率

0.00%

发文量

122

审稿时长

25 days

期刊介绍： The Journal of Forensic Science International Genetics Supplement Series is the perfect publication vehicle for the proceedings of a scientific symposium, commissioned thematic issues, or for disseminating a selection of invited articles. The Forensic Science International Genetics Supplement Series is part of a duo of publications on forensic genetics, published by Elsevier on behalf of the International Society for Forensic Genetics.