紫锥菊对小儿上呼吸道感染无效

Evidence-based Healthcare Pub Date : 2004-06-01 DOI:10.1016/j.ehbc.2004.03.010

Arch G Mainous III PhD (Commentary Author)

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引用次数: 4

摘要

问题紫锥菊在减少儿童上呼吸道感染的持续时间和严重程度方面的安全性和有效性如何？研究设计多中心随机对照试验。主要结果与安慰剂相比，上呼吸道感染儿童紫锥菊症状的持续时间或严重程度没有显著差异（症状的中位持续时间（95%CI）：紫锥菊9天（8-10天）与安慰剂9天（8-10天）；P=0.89；症状的中位严重程度（95%CI）：紫锥菊组33（29-40），安慰剂组33（30-38）；P=0.69）。与安慰剂相比，接受紫锥菊治疗的儿童出现皮疹的人数明显更多（皮疹报告：24例紫锥菊，10例安慰剂；P=0.008）。作者的结论紫锥菊对2至11岁儿童的上呼吸道感染无效。

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Echinacea purpurea is ineffective for upper respiratory tract infections in children

Question

How safe and effective is Echinacea purpurea at reducing the duration and severity of upper respiratory tract infections in children?

Study design

Multicentre randomised controlled trial.

Main results

There was no significant difference in duration or severity of symptoms with Echinacea purpurea compared with placebo in children with upper respiratory tract infection (median duration of symptoms (95% CI): 9 days (8 to 10 days) with Echinacea vs. 9 days (8 to 10 days) with placebo; P=0.89; median severity of symptoms (95% CI): 33 (29 to 40) with Echinacea vs. 33 (30 to 38) with placebo; P=0.69). Rash occurred in significantly more children receiving Echinacea compared with placebo (reports of rash: 24 with Echinacea v 10 with placebo; P=0.008).

Authors’ conclusions

Echinacea purpurea is ineffective for treating upper respiratory tract infections in children aged 2 to 11 years.

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来源期刊

Evidence-based Healthcare

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