儿童龋齿与健康状况不佳和中年衰老速度加快有关。

IF 1.8 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE
Begoña Ruiz PhD, Jonathan M. Broadbent PhD, W. Murray Thomson PhD, Sandhya Ramrakha PhD, Terrie E. Moffitt PhD, Avshalom Caspi PhD, Richie Poulton PhD
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引用次数: 0

摘要

目的:儿童龋齿与成年后自我评定的总体健康状况较差有关,但尚不清楚这是否适用于身体健康和衰老。这项研究的目的是确定5岁的龋齿是否与(a)身体健康状况不佳的生物标志物和(b)45岁时的衰老速度(PoA)有关 年。方法:参与者是达尼丁多学科健康与发展研究出生队列的成员。在45岁时,94.1%(n = 938人)参加了活动。收集了5岁年龄段龋齿经历和45岁年龄段健康生物标志物的数据。PoA记录了从26岁到45岁心血管、代谢、肾脏、免疫、牙齿和肺部系统与年龄相关的下降 年。我们使用(a)广义估计方程来检验5岁龋齿与45岁之前身体健康状况不佳之间的关系 以及(b)检验5岁年龄的龋齿是否与PoA相关的普通最小二乘回归。分析对性别、围产期健康、儿童SES和儿童IQ进行了调整。结果:5岁时的高龋齿经历与某些代谢异常的高风险相关,包括BMI≥30、高腰围和高血清瘦素。那些在5岁时有高龋齿经历的人在45岁时衰老速度更快 结论:口腔健康对健康至关重要。口腔健康状况不佳可能是成年后健康状况不佳的早期信号。应对这两种情况进行更好的综合管理;人口层面的综合预防战略应该是任何卫生系统的基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Childhood caries is associated with poor health and a faster pace of aging by midlife

Childhood caries is associated with poor health and a faster pace of aging by midlife

Objectives

Childhood caries is associated with poorer self-rated general health in adulthood, but it remains unclear whether that holds for physical health and aging. The aim of this study was to identify whether age-5 caries is associated with (a) biomarkers for poor physical health, and (b) the pace of aging (PoA) by age 45 years.

Methods

Participants are members of the Dunedin Multidisciplinary Health and Development Study birth cohort. At age 45, 94.1% (n = 938) of those still alive took part. Data on age-5 caries experience and age-45 health biomarkers were collected. The PoA captures age-related decline across the cardiovascular, metabolic, renal, immune, dental and pulmonary systems from age 26 to 45 years. We used (a) generalized estimating equations to examine associations between age-5 caries and poor physical health by age 45 years, and (b) ordinary least squares regression to examine whether age-5 caries was associated with the PoA. Analyses adjusted for sex, perinatal health, childhood SES and childhood IQ.

Results

High caries experience at age-5 was associated with higher risk for some metabolic abnormalities, including BMI ≥30, high waist circumference, and high serum leptin. Those with high caries experience at age-5 were aging at a faster rate by age 45 years than those who had been caries-free.

Conclusions

Oral health is essential for wellbeing. Poor oral health can be an early signal of a trajectory towards poor health in adulthood. Management for both conditions should be better-integrated; and integrated population-level prevention strategies should be foundational to any health system.

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来源期刊
Journal of public health dentistry
Journal of public health dentistry 医学-公共卫生、环境卫生与职业卫生
CiteScore
3.80
自引率
4.30%
发文量
69
审稿时长
6-12 weeks
期刊介绍: The Journal of Public Health Dentistry is devoted to the advancement of public health dentistry through the exploration of related research, practice, and policy developments. Three main types of articles are published: original research articles that provide a significant contribution to knowledge in the breadth of dental public health, including oral epidemiology, dental health services, the behavioral sciences, and the public health practice areas of assessment, policy development, and assurance; methods articles that report the development and testing of new approaches to research design, data collection and analysis, or the delivery of public health services; and review articles that synthesize previous research in the discipline and provide guidance to others conducting research as well as to policy makers, managers, and other dental public health practitioners.
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