{"title":"珀斯大都会医院不同种族女性死产原因的回顾性研究。","authors":"Kriti Sharma, Saiuj Bhat, Sangeeta Malla Bhat","doi":"10.1111/ajo.13761","DOIUrl":null,"url":null,"abstract":"<div>\n \n <section>\n \n <h3> Background</h3>\n \n <p>Most published reports analysing the differences in causation of stillbirth between different ethnic groups focus on stillbirth risk factors, with a paucity of data comparing actual causes of stillbirth.</p>\n </section>\n \n <section>\n \n <h3> Aims</h3>\n \n <p>To determine whether causes of stillbirth differ between Caucasian and non-Caucasian ethnic groups in an Australian context.</p>\n </section>\n \n <section>\n \n <h3> Materials and Methods</h3>\n \n <p>Data from all stillbirths occurring at 20 or more completed weeks of gestation between 1 January 2010 and 31 December 2020 at a secondary level, outer metropolitan hospital, were analysed in this retrospective case series. Causes of stillbirth as determined by perinatal autopsy and placental histopathology were categorised using the Perinatal Society of Australia and New Zealand Perinatal Death Classification and compared between Caucasian and non-Caucasian groups.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Ninety-two stillbirths (0.7% of all births) were identified during the study period. A greater proportion of non-Caucasian women had small for gestation age placentas compared to Caucasian women (<i>n</i> = 22/43 (51%) vs <i>n</i> = 12/49 (24%); <i>P</i> = 0.025). A greater proportion of stillbirths were caused by hypoxic peripartum death in non-Caucasian than in Caucasian women (<i>n</i> = 4/43 (9%) vs <i>n</i> = 0/49 (0%); <i>P</i> = 0.044), and a greater prevalence of placental dysfunction was seen in the non-Caucasian cohort compared to Caucasian women (<i>n</i> = 14/43 (33%) vs <i>n</i> = 8/49 (16%); <i>P</i> = 0.057).</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>The differences observed in causes of stillbirth between Caucasian and non-Caucasian women are hypothesis generating and warrant further larger-scale, multi-centred studies using standardised definitions and classification systems to determine whether these differences persist in a more representative sample.</p>\n </section>\n </div>","PeriodicalId":55429,"journal":{"name":"Australian & New Zealand Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Causes of stillbirth in ethnically diverse women in a Perth metropolitan hospital: A retrospective study\",\"authors\":\"Kriti Sharma, Saiuj Bhat, Sangeeta Malla Bhat\",\"doi\":\"10.1111/ajo.13761\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>Most published reports analysing the differences in causation of stillbirth between different ethnic groups focus on stillbirth risk factors, with a paucity of data comparing actual causes of stillbirth.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Aims</h3>\\n \\n <p>To determine whether causes of stillbirth differ between Caucasian and non-Caucasian ethnic groups in an Australian context.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Materials and Methods</h3>\\n \\n <p>Data from all stillbirths occurring at 20 or more completed weeks of gestation between 1 January 2010 and 31 December 2020 at a secondary level, outer metropolitan hospital, were analysed in this retrospective case series. Causes of stillbirth as determined by perinatal autopsy and placental histopathology were categorised using the Perinatal Society of Australia and New Zealand Perinatal Death Classification and compared between Caucasian and non-Caucasian groups.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Ninety-two stillbirths (0.7% of all births) were identified during the study period. A greater proportion of non-Caucasian women had small for gestation age placentas compared to Caucasian women (<i>n</i> = 22/43 (51%) vs <i>n</i> = 12/49 (24%); <i>P</i> = 0.025). A greater proportion of stillbirths were caused by hypoxic peripartum death in non-Caucasian than in Caucasian women (<i>n</i> = 4/43 (9%) vs <i>n</i> = 0/49 (0%); <i>P</i> = 0.044), and a greater prevalence of placental dysfunction was seen in the non-Caucasian cohort compared to Caucasian women (<i>n</i> = 14/43 (33%) vs <i>n</i> = 8/49 (16%); <i>P</i> = 0.057).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>The differences observed in causes of stillbirth between Caucasian and non-Caucasian women are hypothesis generating and warrant further larger-scale, multi-centred studies using standardised definitions and classification systems to determine whether these differences persist in a more representative sample.</p>\\n </section>\\n </div>\",\"PeriodicalId\":55429,\"journal\":{\"name\":\"Australian & New Zealand Journal of Obstetrics & Gynaecology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2023-10-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Australian & New Zealand Journal of Obstetrics & Gynaecology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/ajo.13761\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Australian & New Zealand Journal of Obstetrics & Gynaecology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/ajo.13761","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
背景:大多数已发表的分析不同种族群体之间死胎原因差异的报告都集中在死胎风险因素上,缺乏比较死胎实际原因的数据。目的:确定在澳大利亚背景下,高加索和非高加索种族群体的死产原因是否不同。材料和方法:在本回顾性病例系列中,分析了2010年1月1日至2020年12月31日期间在外大都市二级医院妊娠20周或20周以上发生的所有死产的数据。通过围产期尸检和胎盘组织病理学确定的死产原因使用澳大利亚和新西兰围产期协会围产期死亡分类进行分类,并在高加索和非高加索人群之间进行比较。结果:在研究期间发现92例死产(占所有新生儿的0.7%)。与高加索女性相比,非高加索女性中妊娠期胎盘较小的比例更高(n = 22/43(51%)vs n = 12/49(24%);P = 0.025)。与高加索妇女相比,非高加索妇女死产的比例更高(n = 4/43(9%)vs n = 0/49(0%);P = 0.044),与高加索女性相比,非高加索队列中胎盘功能障碍的发生率更高(n = 14/43(33%)vs n = 8/49(16%);P = 0.057)。结论:高加索和非高加索妇女在死产原因方面观察到的差异是假设产生的,需要进一步进行更大规模、多中心的研究,使用标准化的定义和分类系统来确定这些差异是否在更具代表性的样本中持续存在。
Causes of stillbirth in ethnically diverse women in a Perth metropolitan hospital: A retrospective study
Background
Most published reports analysing the differences in causation of stillbirth between different ethnic groups focus on stillbirth risk factors, with a paucity of data comparing actual causes of stillbirth.
Aims
To determine whether causes of stillbirth differ between Caucasian and non-Caucasian ethnic groups in an Australian context.
Materials and Methods
Data from all stillbirths occurring at 20 or more completed weeks of gestation between 1 January 2010 and 31 December 2020 at a secondary level, outer metropolitan hospital, were analysed in this retrospective case series. Causes of stillbirth as determined by perinatal autopsy and placental histopathology were categorised using the Perinatal Society of Australia and New Zealand Perinatal Death Classification and compared between Caucasian and non-Caucasian groups.
Results
Ninety-two stillbirths (0.7% of all births) were identified during the study period. A greater proportion of non-Caucasian women had small for gestation age placentas compared to Caucasian women (n = 22/43 (51%) vs n = 12/49 (24%); P = 0.025). A greater proportion of stillbirths were caused by hypoxic peripartum death in non-Caucasian than in Caucasian women (n = 4/43 (9%) vs n = 0/49 (0%); P = 0.044), and a greater prevalence of placental dysfunction was seen in the non-Caucasian cohort compared to Caucasian women (n = 14/43 (33%) vs n = 8/49 (16%); P = 0.057).
Conclusions
The differences observed in causes of stillbirth between Caucasian and non-Caucasian women are hypothesis generating and warrant further larger-scale, multi-centred studies using standardised definitions and classification systems to determine whether these differences persist in a more representative sample.
期刊介绍:
The Australian and New Zealand Journal of Obstetrics and Gynaecology (ANZJOG) is an editorially independent publication owned by the Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG) and the RANZCOG Research foundation. ANZJOG aims to provide a medium for the publication of original contributions to clinical practice and/or research in all fields of obstetrics and gynaecology and related disciplines. Articles are peer reviewed by clinicians or researchers expert in the field of the submitted work. From time to time the journal will also publish printed abstracts from the RANZCOG Annual Scientific Meeting and meetings of relevant special interest groups, where the accepted abstracts have undergone the journals peer review acceptance process.