肝棘球蚴病。

IF 1.8 4区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY
Visceral Medicine Pub Date : 2023-10-01 Epub Date: 2023-09-25 DOI:10.1159/000533807
Virandera Pal Bhalla, Souvik Paul, Ernst Klar
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引用次数: 0

摘要

背景:棘球蚴病又称棘球蚴症,是一种由绦虫引起的人畜共患寄生虫病。它在全球范围内发行。长期以来,这被认为是“第三世界”消毒不力的问题,没有得到应有的重视。然而,它在澳大利亚和新西兰等国以及最近在中欧国家的出现意味着它被列入世界卫生组织被忽视疾病名单,最近成为广泛流行病学研究的主题,并获得了更多的研究资金。总结:诊断仍然基于流行地区的临床表现,并与常规包括超声和CT扫描在内的典型成像结果相证实。一些中心已经使用血清学测试来支持诊断。治疗取决于涉及的部位,从等待和观察到广泛的根治性手术都有可能。所有治疗的共同因素是添加阿苯达唑,这是所有治疗方案的重要基石。尽管阿苯达唑已经使用了相当长的时间,但在剂量、持续时间和治疗时间方面仍然没有达成共识。关键信息:尽管人们对棘球蚴病的生命周期有很好的了解,而且公共卫生标准不断提高,但它仍然是一个重大的全球健康问题。尽管诊断简单且不昂贵,但治疗有时可能很复杂。在所有治疗方案中加入阿苯达唑是一个重要的进展,但关于其使用期限的确切指导方针仍在等待中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hydatid Disease of the Liver.

Background: Echinococcosis also known as hydatid disease is a zoonotic parasitic disease caused by a tapeworm. It has a worldwide distribution. For long, it was thought to be a problem of the poorly sanitized "third world" and not given the importance it deserved. However, its occurrence in countries like Australia and New Zealand and recently in countries in Central Europe has meant that it is included in a WHO list of neglected diseases, has recently been the subject of extensive epidemiological studies, and has been the recipient of increased research funding.

Summary: The diagnosis is still based on clinical presentation in an endemic area corroborated with typical findings on imaging which routinely include ultrasound and CT scan. Serological tests have been used in some centers to support the diagnosis. Treatment depends on the site of involvement and can vary from wait and watch to extensive radical surgical procedures. The common element of all treatments is the addition of albendazole which forms an essential cornerstone of all treatment protocols. Inspite having been used for a fairly long time, there is still no consensus on the dose, duration, and timing of therapy with albendazole.

Key message: Hydatid disease continues to be a significant global health problem inspite of a good understanding of its life cycle and rising standards of public sanitation. Though diagnosis is straightforward and not expensive, treatment can sometimes be complicated. The addition of albendazole to all treatment protocols is an important advance, but firm guidelines on duration of its use are still awaited.

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来源期刊
Visceral Medicine
Visceral Medicine Medicine-Surgery
CiteScore
4.50
自引率
0.00%
发文量
40
期刊介绍: This interdisciplinary journal is unique in its field as it covers the principles of both gastrointestinal medicine and surgery required for treating abdominal diseases. In each issue invited reviews provide a comprehensive overview of one selected topic. Thus, a sound background of the state of the art in clinical practice and research is provided. A panel of specialists in gastroenterology, surgery, radiology, and pathology discusses different approaches to diagnosis and treatment of the topic covered in the respective issue. Original articles, case reports, and commentaries make for further interesting reading.
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