颅脑减压/半骨切除术在外伤性脑损伤治疗中的作用:回顾性研究

Sudhir Singh, Rajat D Maheshwari, Anupam Surendran, A. Sharath
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引用次数: 0

摘要

简介:头部损伤是任何类型的创伤的最常见的结果之一,成为世界范围内发病率和死亡率的主要原因。治疗严重头部损伤患者的关键因素是防止病情的进展和对脑细胞的继发性损伤。重型颅脑损伤的治疗遵循了各种方案,从保守的医疗管理到手术方法,如DC/半颅切除术(DC)。DC是一种切除部分颅骨的手术方法,使脑实质有空间扩张,降低颅内压(ICP)。有各种各样的因素导致了DC的结果。目的:探讨影响DC/半脑切除术预后的各种因素。材料和方法:2017年5月至2021年4月,在印度中央邦甘地医学院研究所和相关的Hamidia医院进行了一项回顾性描述性研究。本研究纳入了100例中重度颅脑损伤患者。使用卡方检验比较年龄、术前GCS、手术时间、术前瞳孔反应和中线移位(MLS)等变量的生存/死亡和有利/不利结果。结果:参与者平均年龄45±14岁。统计分析显示,年龄、术前格拉斯哥昏迷评分(GCS)、手术时间、就诊时瞳孔反应和术前MLS(生存/死亡和有利/不利结果)等变量均有显著结果。结论:年龄越小,术前GCS越好,手术越早,就诊时瞳孔反应性越强,术前MLS越少,采用DC/半颅骨切除术降低颅内压升高具有积极的预后益处。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of Decompressive Craniectomy/ Hemicraniectomy in the Management of Traumatic Brain Injury: A Retrospective Study
Introduction: Head injury is one of the most common outcomes of any kind of trauma becoming the major cause of morbidity and mortality worldwide. The critical element in the treatment of patients with severe head injuries is to prevent the progression of the condition and secondary insult to brain cells. Various protocols are followed for the treatment of severe head injury starting from conservative medical management to surgical approaches like DC/hemicraniectomy (DC). The DC is a surgical method of removal of part of skull bone so that the brain parenchyma gets space to expand and the Intracranial Pressure (ICP) can get reduced. There are various factors that contribute to the outcome of DC. Aim: To determine the various factors that affect the outcome of DC/hemicraniectomy. Materials and Methods: A retrospective descriptive study was conducted in the Institute of Gandhi Medical College and associated Hamidia hospital, Madhya Pradesh, India from May 2017 to April 2021. Hundred patients with moderate to severe head injury who underwent primary DC were included in this study. The variables such as age, preoperative GCS, the timing of surgery, preoperative pupillary reaction, and MidLine Shift (MLS) were compared in terms of survival/death and favourable/ unfavourable outcomes using the chi-square test. Results: The mean age of participants was 45±14 years. Statistical analysis showed significant results for the variables like age, preoperative the Glasgow Coma Scale (GCS), timing of the surgery, pupillary reaction at presentation, and preoperative MLS in terms of survival/death and favourable/ unfavourable outcomes. Conclusion: Younger age group, better preoperative GCS, early surgery, reactive pupils at presentation, and less preoperative MLS have positive outcome benefits with the DC/ hemicraniectomy to reduce the raised ICP.
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