Anđela Tošić, Tijana Stankovic, T. Ilić, S. Savić, I. Pantelić
{"title":"摩擦学试验的当前作用:争取医药和化妆品的充分表征","authors":"Anđela Tošić, Tijana Stankovic, T. Ilić, S. Savić, I. Pantelić","doi":"10.5937/arhfarm73-43515","DOIUrl":null,"url":null,"abstract":"Tribology investigates the events that happen on the surfaces of two substances/objects that are in direct or indirect contact through assessing friction, lubrication and/or wear. In particular, friction measurements could provide the information on the textural characteristics of (per)oral pharmaceutical preparations and contribute to the understanding of palatability. On the other hand, tribological tests have been more intensively used to characterize topical preparations (pharmaceutical, cosmetic), giving a thorough insight into the tactile and texture properties of these preparations. However, these tests are often combined with rheological, textural, and certain biophysical approaches. Additionally, the materials used for constructing artificial joints and articular cartilages are true tribological systems, developed and optimized in order to have properties that resemble the natural ones. Since tribological studies can be used to assess a wide range of drug dosage forms and products in general, the equipment used may be quite diverse. Accordingly, a special section of this work is committed to the description of the testing equipment's specifications and the applied protocols. The investigation of recently regulatory discovered phenomena, such as transformation/metamorphosis of the vehicle/base of topical preparations, have brought tribology back into focus as a potential assessment method.","PeriodicalId":39173,"journal":{"name":"Arhiv za Farmaciju","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Current role of tribological tests: Striving for full characterization of medicinal and cosmetic products\",\"authors\":\"Anđela Tošić, Tijana Stankovic, T. Ilić, S. Savić, I. Pantelić\",\"doi\":\"10.5937/arhfarm73-43515\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Tribology investigates the events that happen on the surfaces of two substances/objects that are in direct or indirect contact through assessing friction, lubrication and/or wear. In particular, friction measurements could provide the information on the textural characteristics of (per)oral pharmaceutical preparations and contribute to the understanding of palatability. On the other hand, tribological tests have been more intensively used to characterize topical preparations (pharmaceutical, cosmetic), giving a thorough insight into the tactile and texture properties of these preparations. However, these tests are often combined with rheological, textural, and certain biophysical approaches. Additionally, the materials used for constructing artificial joints and articular cartilages are true tribological systems, developed and optimized in order to have properties that resemble the natural ones. Since tribological studies can be used to assess a wide range of drug dosage forms and products in general, the equipment used may be quite diverse. Accordingly, a special section of this work is committed to the description of the testing equipment's specifications and the applied protocols. The investigation of recently regulatory discovered phenomena, such as transformation/metamorphosis of the vehicle/base of topical preparations, have brought tribology back into focus as a potential assessment method.\",\"PeriodicalId\":39173,\"journal\":{\"name\":\"Arhiv za Farmaciju\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Arhiv za Farmaciju\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5937/arhfarm73-43515\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Pharmacology, Toxicology and Pharmaceutics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Arhiv za Farmaciju","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5937/arhfarm73-43515","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
Current role of tribological tests: Striving for full characterization of medicinal and cosmetic products
Tribology investigates the events that happen on the surfaces of two substances/objects that are in direct or indirect contact through assessing friction, lubrication and/or wear. In particular, friction measurements could provide the information on the textural characteristics of (per)oral pharmaceutical preparations and contribute to the understanding of palatability. On the other hand, tribological tests have been more intensively used to characterize topical preparations (pharmaceutical, cosmetic), giving a thorough insight into the tactile and texture properties of these preparations. However, these tests are often combined with rheological, textural, and certain biophysical approaches. Additionally, the materials used for constructing artificial joints and articular cartilages are true tribological systems, developed and optimized in order to have properties that resemble the natural ones. Since tribological studies can be used to assess a wide range of drug dosage forms and products in general, the equipment used may be quite diverse. Accordingly, a special section of this work is committed to the description of the testing equipment's specifications and the applied protocols. The investigation of recently regulatory discovered phenomena, such as transformation/metamorphosis of the vehicle/base of topical preparations, have brought tribology back into focus as a potential assessment method.