抗逆转录病毒治疗下HIV/AIDS传播的地方性分析

S. Baba, I. Mohammed, S. Christopher
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引用次数: 1

摘要

本文提出了一个动态模型,研究抗逆转录病毒治疗对人类免疫缺陷病毒(HIV)/获得性免疫缺陷综合征(AIDS)传播的影响。导出了模型的基本定性性质。结果表明,当基本繁殖数小于1时,该模型不会出现后向分叉,因此可以根除疾病。还得出了为可能根除疾病而需要达到的抗逆转录病毒治疗的临界水平。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Endemic analysis of HIV/AIDS transmission in the presence of antiretroviral therapy
This paper presents a dynamical model that studies the effect of anti-retroviral therapy on human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) transmission. Basic qualitative properties of the model are derived. The model is shown not to exhibit backward bifurcation and thus, disease eradication is possible when the basic reproduction number is less than unity. A critical level of anti-retroviral therapy administration that needs to be achieved for possible disease eradication was also derived.
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