评价心理社会压力源与心血管疾病之间关系的候选生物标志物:简要综述

IF 0.6 Q4 PSYCHOLOGY, CLINICAL

European Journal of Mental Health Pub Date : 2023-01-01 DOI:10.5708/ejmh.18.2023.0005

H. Ayari, M. Zeller

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引用次数: 0

摘要

引言:社会心理压力源与心血管疾病之间的关联已被提出。目的:本综述旨在从文献资料中评估在心理社会背景下使用新的生物标志物对心血管疾病发生或预后的相关性。方法:我们选择考虑可能诱发或影响心血管疾病结局的心理压力源(职业压力、经济压力、婚姻压力、社会孤立等)的广泛描述。我们分析了证实候选生物标志物(如皮质醇、内皮功能障碍、促炎细胞因子、适应负荷和心血管疾病)之间联系的文献数据。结果和结论:在本研究中，我们发现皮质醇、内皮功能障碍、促炎细胞因子与心理社会压力下心血管疾病的发病率或预后之间存在联系。适应负荷指数也被确定为评估施加在身体上的累积社会心理压力源负担的相关工具。

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Candidate Biomarkers to Evaluate the Association Between Psychosocial Stressors and Cardiovascular Diseases : A Short Review

Introduction: The association between psychosocial stressors and cardiovascular diseases had been suggested. Aims: This review was performed to assess, from literature data, the pertinence of using new biomarkers in the occurrence or prognosis of cardiovascular diseases in a psychosocial context. Methods: We choose to consider wide-ranging descriptions of psychological stressors (occupational stress, financial strain, marital stress, social isolation, etc.) that may induce or influence the cardiovascular diseases’ outcome. We addressed literature data confirming the link between candidate biomarkers, such as cortisol, endothelial dysfunction, pro-inflammatory cytokines, allostatic load, and cardiovascular diseases. Results and Conclusion: Herein we showed a link between cortisol, endothelial dysfunction, pro-inflammatory cytokines, and the incidence or prognosis of cardiovascular diseases in a psychosocial context of stress. Allostatic load index was also identified as a pertinent tool in the assessment of the cumulative psychosocial stressors’ burden exerted on the body.

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来源期刊

European Journal of Mental Health PSYCHOLOGY, CLINICAL-

CiteScore

0.70

自引率

14.30%

发文量

期刊介绍： The European Journal of Mental Health, an open-access, peer reviewed, interdisciplinary, professional journal concerned with mental health, personal well-being and its supporting ecosystems that acknowledge the importance of people’s interactions with their environments, established in 2006, is published on 280 pages per volume in English and German by the Semmelweis University Institute of Mental Health. The journal’s professional oversight is provided by the Editor-in-Chief and an international Editorial Board, assisted by an Advisory Board. The semiannual journal, with issues appearing in June and December, is published in Budapest. The journal aims at the dissemination of the latest scientific research on mental health and well-being in Europe. It seeks novel, integrative and comprehensive, applied as well as theoretical articles that are inspiring for professionals and practitioners with different fields of interest: social and natural sciences, humanities and different segments of mental health research and practice. The primary thematic focus of EJMH is the social-ecological antecedents of mental health and foundations of human well-being. Most specifically, the journal welcomes contributions that present high-quality, original research findings on well-being and mental health across the lifespan and in historical perspective.