在国家免疫规划中引入七价结合疫苗之前，哥斯达黎加中耳炎儿童的肺炎链球菌上呼吸道传播

疫苗(英文) Pub Date : 2013-05-22 DOI:10.4236/WJV.2013.32007

Catalina Ulloa, A. Pereira, Carolina Soley, N. Porat, A. Abdelnour, R. Dagan, A. Arguedas

{"title":"在国家免疫规划中引入七价结合疫苗之前，哥斯达黎加中耳炎儿童的肺炎链球菌上呼吸道传播","authors":"Catalina Ulloa, A. Pereira, Carolina Soley, N. Porat, A. Abdelnour, R. Dagan, A. Arguedas","doi":"10.4236/WJV.2013.32007","DOIUrl":null,"url":null,"abstract":"Objective: The \naim of this study was to analyze the NP/OP S. \npneumoniae serotype distribution and potential vaccine coverage in Costa \nRican children with Otitis Media (OM) before the introduction of PCV-7 in the National Immunization Program \n(NIP). Methods: Between 2002 and \n2006, NP and OP samples were obtained from 641 children from 6 to 79 months of \nage, at the time of OM diagnosis. S. \npneumoniae serotyping and antimicrobial susceptibility were performed. Results: 386 S. pneumoniae isolates were recovered. The most common S. pneumoniae serotypes (ST) were: ST \n6B, ST 14, ST 19F. \nPenicillin non-susceptibility was observed among 57% of the isolates obtained \nfrom children Conclusions: S. pneumoniae was isolated from the NP \nand/or OP in the majority (59%) of studied children with OM. At a statistical \nsignificant level, only serotype 3 was more frequently isolated among children \n>24 months of age. Antibiotic non-susceptibility and MDR were significantly \nhigher in children","PeriodicalId":57190,"journal":{"name":"疫苗(英文)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2013-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Streptococcus pneumoniae Upper Respiratory Carriage in Costa Rican Children with Otitis Media before the Introduction of the Heptavalent Conjugated Vaccine in the National Immunization Program\",\"authors\":\"Catalina Ulloa, A. Pereira, Carolina Soley, N. Porat, A. Abdelnour, R. Dagan, A. Arguedas\",\"doi\":\"10.4236/WJV.2013.32007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: The \\naim of this study was to analyze the NP/OP S. \\npneumoniae serotype distribution and potential vaccine coverage in Costa \\nRican children with Otitis Media (OM) before the introduction of PCV-7 in the National Immunization Program \\n(NIP). Methods: Between 2002 and \\n2006, NP and OP samples were obtained from 641 children from 6 to 79 months of \\nage, at the time of OM diagnosis. S. \\npneumoniae serotyping and antimicrobial susceptibility were performed. Results: 386 S. pneumoniae isolates were recovered. The most common S. pneumoniae serotypes (ST) were: ST \\n6B, ST 14, ST 19F. \\nPenicillin non-susceptibility was observed among 57% of the isolates obtained \\nfrom children Conclusions: S. pneumoniae was isolated from the NP \\nand/or OP in the majority (59%) of studied children with OM. At a statistical \\nsignificant level, only serotype 3 was more frequently isolated among children \\n>24 months of age. Antibiotic non-susceptibility and MDR were significantly \\nhigher in children\",\"PeriodicalId\":57190,\"journal\":{\"name\":\"疫苗(英文)\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2013-05-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"疫苗(英文)\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.4236/WJV.2013.32007\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"疫苗(英文)","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4236/WJV.2013.32007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 1

摘要

目的:分析哥斯达黎加中耳炎(OM)儿童在国家免疫规划(NIP)引入PCV-7之前的NP/OP肺炎链球菌血清型分布和潜在疫苗覆盖率。方法:2002年至2006年间，对641例6 ~ 79月龄儿童进行OM诊断时的NP和OP样本采集。进行肺炎链球菌血清分型及药敏试验。结果:共分离出386株肺炎链球菌。最常见的肺炎链球菌血清型(ST)为:ST 6B、ST 14、ST 19F。结论:肺炎链球菌在大多数(59%)研究的OM患儿中从NP和/或OP分离。在有统计学意义的水平上，只有血清3型在0 ~ 24月龄的儿童中更常见。儿童的抗生素不敏感性和耐多药发生率明显高于儿童

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Streptococcus pneumoniae Upper Respiratory Carriage in Costa Rican Children with Otitis Media before the Introduction of the Heptavalent Conjugated Vaccine in the National Immunization Program

Objective: The aim of this study was to analyze the NP/OP S. pneumoniae serotype distribution and potential vaccine coverage in Costa Rican children with Otitis Media (OM) before the introduction of PCV-7 in the National Immunization Program (NIP). Methods: Between 2002 and 2006, NP and OP samples were obtained from 641 children from 6 to 79 months of age, at the time of OM diagnosis. S. pneumoniae serotyping and antimicrobial susceptibility were performed. Results: 386 S. pneumoniae isolates were recovered. The most common S. pneumoniae serotypes (ST) were: ST 6B, ST 14, ST 19F. Penicillin non-susceptibility was observed among 57% of the isolates obtained from children Conclusions: S. pneumoniae was isolated from the NP and/or OP in the majority (59%) of studied children with OM. At a statistical significant level, only serotype 3 was more frequently isolated among children >24 months of age. Antibiotic non-susceptibility and MDR were significantly higher in children

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

疫苗(英文)

自引率

0.00%

发文量