{"title":"骨质疏松-骨质疏松伴佝偻病,一种罕见的矛盾关联","authors":"K. Umesh, J. Rajesh","doi":"10.5580/45e","DOIUrl":null,"url":null,"abstract":"Osteopetrosis is an extremely rare inhereditory bone disorder, in which defective bone resorption by osteoclasts leads to excessive bone deposition. Though, there is usually calcium excess in osteopetrosis, rickets has been described rarely as a paradoxical complication of infantile osteopetrosis and it results from the inability of the osteoclasts to maintain a normal calcium-phosphorus balance in the extracellular fluid. It is rare paradoxical association. We report two cases of infantile osteopetrosis complicated by rickets and subsequent management issues.","PeriodicalId":75037,"journal":{"name":"The Internet journal of pediatrics and neonatology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Osteopetrorickets- Osteopetrosis with rickets, a rare paradoxical association\",\"authors\":\"K. Umesh, J. Rajesh\",\"doi\":\"10.5580/45e\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Osteopetrosis is an extremely rare inhereditory bone disorder, in which defective bone resorption by osteoclasts leads to excessive bone deposition. Though, there is usually calcium excess in osteopetrosis, rickets has been described rarely as a paradoxical complication of infantile osteopetrosis and it results from the inability of the osteoclasts to maintain a normal calcium-phosphorus balance in the extracellular fluid. It is rare paradoxical association. We report two cases of infantile osteopetrosis complicated by rickets and subsequent management issues.\",\"PeriodicalId\":75037,\"journal\":{\"name\":\"The Internet journal of pediatrics and neonatology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2008-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Internet journal of pediatrics and neonatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5580/45e\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Internet journal of pediatrics and neonatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5580/45e","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Osteopetrorickets- Osteopetrosis with rickets, a rare paradoxical association
Osteopetrosis is an extremely rare inhereditory bone disorder, in which defective bone resorption by osteoclasts leads to excessive bone deposition. Though, there is usually calcium excess in osteopetrosis, rickets has been described rarely as a paradoxical complication of infantile osteopetrosis and it results from the inability of the osteoclasts to maintain a normal calcium-phosphorus balance in the extracellular fluid. It is rare paradoxical association. We report two cases of infantile osteopetrosis complicated by rickets and subsequent management issues.