尼日尔三角洲大学教学医院新生儿破伤风的5年回顾性研究

O. Peterside, C. Duru, B. O. George
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引用次数: 11

摘要

背景:新生儿破伤风(NNT)虽然可以预防,但在尼日利亚等发展中国家仍然是发病率和死亡率的重要原因。目的:在尼日利亚巴耶尔萨州尼日尔三角洲大学教学医院(NDUTH)的儿科部门进行了一项研究,以突出该州的NNT负担,并提供可能有助于根除该疾病的解决方案。方法:在5年期间(2007年5月至2012年4月),回顾性研究了NDUTH儿科收治的所有NNT病例。结果:研究期间共纳入4780名儿童。新生儿破伤风占40例(0.84%),男女比例为1:2,平均年龄8.3天。34名(77.3%)母亲没有产前护理,而是在医疗机构外分娩。使用剃刀剪断脐带占37.5%,使用毛线扎脐带占15.0%。17名(42.5%)母亲没有接受过正规教育。40例患者中有15例死亡,病死率为37.5%。男性病死率(46.2%)高于女性(33.3%)。NNT占所有儿科死亡的3.5%,占新生儿死亡的9.0%。结论:NNT仍是该环境中发病和死亡的重要原因。应加强旨在消除这一社会祸害的努力,并应作出更多努力,提高所有妇女甚至在达到生育年龄之前接种破伤风疫苗的覆盖率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neonatal Tetanus At The Niger Delta University Teaching Hospital: A 5 Year Retrospective Study
Background : Neonatal tetanus (NNT) though preventable, remains a significant cause of morbidity and mortality in developing countries like Nigeria.Objective: A study was carried out in the Paediatrics unit of the Niger Delta University Teaching Hospital (NDUTH), Bayelsa State, Nigeria to highlight the burden of NNT in the state and proffer solutions which may be useful in its eradication.Methodology: Over a 5 year period (from May 2007 to April 2012), all cases of NNT admitted into the Paediatrics unit of the NDUTH were retrospectively studied.Results: A total of 4780 children were admitted during the study period. Neonatal tetanus accounted for 40 (0.84%) of these admissions, with a male to female ratio of 1:2, and a mean age of 8.3 days. Thirty four (77.3%) of the mothers had no antenatal care and delivered outside health facilities. Razor blade was used to cut the umbilical cord in 37.5% of the cases and hair thread was used to tie the cord in 15.0%. Seventeen (42.5%) of the mothers had no formal education. Fifteen of the 40 patients died, giving a case fatality rate of 37.5%. The case fatality rate for males (46.2%) was higher than that for females (33.3%). NNT accounted for 3.5% of all Paediatric deaths and 9.0% of neonatal deaths. Conclusion: NNT is still a significant cause of morbidity and mortality in this environment. Efforts aimed at eradication of this social scourge should be intensified and more efforts should be geared towards improving the anti-tetanus vaccine coverage rate of all women even before they get to child bearing age.
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