起搏器胶囊治疗肠蠕动缺陷及吞咽困难

Ayse Ulusoy
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引用次数: 0

摘要

有许多精神或中枢疾病与胃肠系统运动障碍或吞咽困难有关。吞咽困难是由不同病理组合引起的一组症状。原因可能是心理上的、神经上的、机械上的或肌肉上的。吞咽困难有两种类型:口咽吞咽困难或食管吞咽困难。营养缺乏或误吸可能导致并发症,这种情况可能是致命的。吞咽障碍的对症治疗非常重要,可以提高生活质量。提出了一种修改GIS蠕动的新方法。我们假设电刺激治疗肠蠕动不足。当胃肠道起搏器胶囊被吞下时,它会在通过管腔时开始电刺激。这样食道的平滑肌就会收缩。为了模拟食管肌收缩的运动,电刺激必须有节奏。经皮电刺激获得吞咽行为是可能的。维塔斯汀治疗在这些患者中给予了最积极的结果。在胃肠起搏器胶囊的贡献下,将开发一种新的、救命的方法来重新安排胃肠道蠕动功能障碍,作为减肥手术相关的胃肠道蠕动功能障碍,特别是神经性厌食症。在这次演讲中,我们将讨论现有的研究,然后是可预测的未来项目。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Treatment of peristaltic defect and difficulty swallowing with pace-maker capsule -
There are lot of psychiatric or central illnesses about gastrointestinal system motility deficiency or difficulty of swallowing. Dysphagia is a group of symptoms caused by a combination of different pathologies. The reason could be psychological, neurogenic, mechanic or myogenic. There are 2 types of dysphagia: oropharyngeal or esophageal dysphagia. Lack of nutrients or aspiration may cause complication and this situation may be fatal. Symptomatic treatment of swallowing disorders are very important and they enhance the quality of life. A new method have been proposed for modifying GIS peristalsis. We hypothesized the treatment of peristaltic movement deficiency by electric stimulation. When the gastrointestinal pace-maker capsule is swallowed, it will start electric stimulation while it passes over the lumen. Thus smooth muscles of esophagus will contract. To mimic the movement of esophageal muscle contraction electric stimulation must be rhythmic. It is possible to gain the behavior of swallowing by transcutaneus electric stimulation. Vitalstim therapy gave the most positive results in these patients. With contribution of gastrointestinal pace-maker capsule, a novel and lifesaver method will developed for re-arrangement of peristaltic movement deficiency as bariatric surgery related GIS peristalsis deficiency and particularly anorexia nervosa bulimia. In this presentation, we will talk about existent studies and then predictable projects of the future.
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