孟加拉国坦盖尔市尿路感染细菌菌株的抗生素耐药模式

Q3 Biochemistry, Genetics and Molecular Biology
Nishat Akther, Farjana Hira, A. Khatun, Shawon Md, S. Abdullah, Esrat Shorna, Ashekul Islam, K. Islam, N. Hossain
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引用次数: 0

摘要

背景:抗菌素耐药性已成为全世界一个令人担忧的问题。此外,在发展中国家以及孟加拉国,由于缺乏研究,面临着这一严重问题。抗生素耐药性在引起尿路感染的细菌病原体中普遍存在。全世界有30%的人患有尿路感染。全世界每年约有1.5亿人经历尿路感染。在治疗尿路感染时,通常是“凭经验”开具抗菌药物治疗,而没有进行抗生素敏感性试验。目的:抗生素耐药性的患病率正在恶化,可能是由于耐多药菌株的增加和滥用广谱抗生素和经验性治疗。本研究旨在确定孟加拉国患者疑似尿路感染细菌的频率和抗生素耐药性模式。方法:对200例尿路感染阳性患者进行多项指标分析,了解其耐药性。结果:经检查,患者尿路感染的耐药率令人担忧,其中以大肠杆菌最多,约占61.8%。200例尿路感染疑似患者中,女性占66%,男性占30%。结论:应指导经验性治疗,控制抗生素耐药性。特别是,发展中国家应该接受挑战,拥有适当的基础设施来监测耐药性,因为耐药性因地区而异。应注重适当的抗生素,合理使用抗生素,通过常见感染预防抗生素耐药。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Antibiotic resistance pattern in the bacterial strains of urinary tract infection in Tangail city, Bangladesh
Background: Antimicrobial resistance has become an alarming issue all over the world. Moreover, in the developing countries as well as in Bangladesh facing this badly due to lack of study. Antibiotic resistance is prevalent among the bacterial pathogens causing urinary tract infections. Urinary tract infections affect >30% of people around the world. Worldwide, about 150 million people experience urinary tract infections each year. Antimicrobial treatment is often prescribed ‘empirically’ without antibiotic susceptibility testing to treat urinary tract infections (UTIs). Aims: The prevalence of antibiotic resistance is worsening, probably because of the increasing number of multidrug-resistant bacterial strains and the indiscriminate use of broad-spectrum antibiotics and empirical treatment. This study aims to determine the frequency and antibiotic resistance pattern of bacteria from suspected UTIs in Bangladeshi patients. Methods: In our study, about 200 samples of positive UTIs patients were analyzed with several parameters to see the antibiotic resistance rate. Result: After examining the patient’s sample of UTIs antibiotic resistance rate is alarming and the most causative bacteria is Escherichia coli which is about 61.8%. Among the 200 urine sample suspected UTI patients 66% and 30% are female and male, respectively. Conclusions: Empirical therapy should be guided to control the antibiotic resistance. Especially, developing country should accept the challenge with proper infrastructure to get the surveillance of resistance, as resistance varies from region to region. Appropriate antibiotics should be focused for the rational use of antibiotics to prevent antibiotics resistance through common infections.
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来源期刊
Journal of Advanced Biotechnology and Experimental Therapeutics
Journal of Advanced Biotechnology and Experimental Therapeutics Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)
CiteScore
1.90
自引率
0.00%
发文量
41
审稿时长
8 weeks
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