注射曲马多与双氯芬酸治疗腹腔镜胆囊切除术术后疼痛:一项比较前瞻性研究

Q4 Medicine
K. Chowdhary, Muzzafar Zaman, R. Yadav, Ashish Choudhary, P. Grewal, A. Bawa, Aliya Shah
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Postoperative analgesic is decided randomly with the help of dice. Pain is measured on visual analog scale (VAS) on 6, 12, 18, and 24 hours. Results: A total of 50 patients, divided in two groups I and II, were taken in this study from December 2016 to December 2017 who underwent laparoscopic cholecystectomy. Group I was given injection diclofenac and group II was given injection tramadol postoperatively for pain management 8 hourly. Both I and II groups were matched in all respect with age, weight, and operative time. Pain relief after diclofenac first dose postoperatively in 8 hours was seen in 7 patients, in 9 to 16 hours in 12 patients, and 17 to 24 hours in 18 patients. Pain relief after tramadol first dose postoperatively in 8 hours was seen in 16 patients, in 9 to 16 hours in 21 patients, and 17 to 24 hours in 25 patients. Postoperatively, patients complained of nausea and vomiting. 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引用次数: 2

摘要

导言:腹腔镜治疗胆结石被认为是当今的金标准治疗,是目前最常见的手术。术后疼痛仍然是腹腔镜胆囊切除术后最常见的主诉之一,应采取适当的镇痛措施,尽量减少副作用。目的:比较注射曲马多与双氯芬酸治疗腹腔镜胆囊切除术后疼痛的疗效。材料与方法:2016年12月至2017年12月,在Maharishi Markandeshwar医学科学与研究学院普通外科学系对50例接受腹腔镜手术的患者进行了一项随机前瞻性研究。术后用骰子随机确定镇痛药。分别于6、12、18、24小时用视觉模拟量表(VAS)测量疼痛。结果:本研究选取2016年12月至2017年12月行腹腔镜胆囊切除术的患者50例,分为I组和II组。ⅰ组术后给予双氯芬酸注射液,ⅱ组术后给予曲马多注射液止痛8 h。I组和II组在年龄、体重、手术时间等各方面均相匹配。7例患者术后第一次给药双氯芬酸后8小时疼痛缓解,12例患者术后9 ~ 16小时疼痛缓解,18例患者术后17 ~ 24小时疼痛缓解。16例患者术后首次给药曲马多后8小时疼痛缓解,21例患者术后9 ~ 16小时疼痛缓解,25例患者术后17 ~ 24小时疼痛缓解。术后患者主诉恶心、呕吐。曲马多输注组的恶心和呕吐发生率高于双氯芬酸输注组。结论:腹腔镜胆囊切除术后疼痛是常见的主诉。应给予患者良好的镇痛药,但应尽量减少副作用。从我们的研究中得出结论,曲马多注射形式是原文1,2助理教授,3-7研究生1-6印度哈里亚纳邦安巴拉Maharishi Markandeshwar医学科学与研究所普通外科学系7印度哈里亚纳邦安巴拉Maharishi Markandeshwar医学科学与研究所微生物学系Muzzafar Zaman,印度哈里亚纳邦安巴拉Maharishi Markandeshwar医学科学与研究所普通外科学系助理教授,电话:+918059931554,电子邮件:muzzafarzaman@yahoo。在缓解疼痛和术后舒适方面,双氯芬酸优于双氯芬酸。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Injectable Tramadol vs Diclofenac for Postoperative Pain Management in Laparoscopic Cholecystectomy Surgery: A Comparative Prospective Study
Introduction: Laparoscopic management of gallstones is considered as the gold standard treatment nowadays and is the most common surgery done in the present scenario. Postoperative pain remains one of the most common complaints after laparoscopic cholecystectomy and should be managed with proper analgesia with minimal side effects. Aim: To compare the efficacy of injectable tramadol and diclofenac in the pain management after laparoscopic cholecystectomy surgery. Materials and methods: A randomized prospective study was done at Maharishi Markandeshwar College of Medical Science & Research in the Department of General Surgery on 50 patients undergoing laparoscopic surgery between December 2016 and December 2017. Postoperative analgesic is decided randomly with the help of dice. Pain is measured on visual analog scale (VAS) on 6, 12, 18, and 24 hours. Results: A total of 50 patients, divided in two groups I and II, were taken in this study from December 2016 to December 2017 who underwent laparoscopic cholecystectomy. Group I was given injection diclofenac and group II was given injection tramadol postoperatively for pain management 8 hourly. Both I and II groups were matched in all respect with age, weight, and operative time. Pain relief after diclofenac first dose postoperatively in 8 hours was seen in 7 patients, in 9 to 16 hours in 12 patients, and 17 to 24 hours in 18 patients. Pain relief after tramadol first dose postoperatively in 8 hours was seen in 16 patients, in 9 to 16 hours in 21 patients, and 17 to 24 hours in 25 patients. Postoperatively, patients complained of nausea and vomiting. Group II having tramadol infusion complained of higher incidence of nausea and vomiting as compared with group I having diclofenac for pain management. Conclusion: Pain after laparoscopic cholecystectomy is a common complaint encountered. Good analgesia should be given to patients but should have minimal side effects. It was concluded from our study that tramadol in injectable form is ORIGINAL ARTICLE 1,2Assistant Professor, 3-7Postgraduate Student 1-6Department of General Surgery, Maharishi Markandeshwar Institute of Medical Sciences & Research, Ambala, Haryana India 7Department of Microbiology, Maharishi Markandeshwar Institute of Medical Sciences & Research, Ambala, Haryana, India Corresponding Author: Muzzafar Zaman, Assistant Professor Department of General Surgery, Maharishi Markandeshwar Institute of Medical Sciences & Research, Ambala, Haryana India, Phone: +918059931554, e-mail: muzzafarzaman@yahoo. com 10.5005/jp-journals-10007-1325 a better option than diclofenac for pain relief and comfortable postoperative period.
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