Atya Hassan Atya Hassan, Sana Gul Sana Gul, Taswar Ali Chandio and Muhammad Ali Minhas Taswar Ali Chandio and Muhammad Ali Minhas
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Further, neither pre nor any post peak was observed. These interpretation express that reactant and product are not involve in the adsorption-desorption process at the surface of Glassy Carbon Electrode (GCE). These remarks suggest that it is diffusion controlled process in the above mentioned system. The interaction of Cu+2 and L-Histidine were not reported before through Cyclic Voltammetry. Furthermore, in this study structure of Cu+2 vs. L-Histidine complex is investigated from a theoretical perspective. Optimization of Cu+2 vs. L-Histidine complex was carried out by DFT method and result verifies that stable structure of Cu+2 vs. L-Histidine complex exist as square planar structure in 1:2 ratio respectively. 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引用次数: 1
摘要
l -组氨酸调节机体功能,参与血红蛋白的合成、组织的修复和免疫系统的增强。本研究采用循环伏安法(CV),以0.1 M氯化钾作为支撑电解质,精确测定Cu+2与l -组氨酸之间的金属配体比例。在CV电位窗口设置在+0.6到-0.4V之间,记录伏安图。扫描速率从50mV/s到300mV/s,记录伏安图。用循环伏安法分析了复合材料的界面性能,并在玻碳电极(GCE)上记录了07个循环的循环伏安图,结果表明阳极峰和阴极峰的峰值电流强度没有变化。此外,没有观察到任何峰前或峰后。这些解释表明,在玻碳电极(GCE)表面,反应物和生成物不参与吸附-解吸过程。说明该系统为扩散控制过程。Cu+2与l -组氨酸的相互作用在循环伏安法中尚未见报道。此外,本研究还从理论角度研究了Cu+2与l -组氨酸络合物的结构。采用DFT方法对Cu+2与l -组氨酸配合物进行了优化,结果表明Cu+2与l -组氨酸配合物分别以1:2的比例呈方形平面结构稳定存在。计算得到的结构与实验结果有一定的相关性,Cu+2与l -组氨酸的1:2比例配合物的伏安图表明其存在于正方形平面几何结构中。
Electrochemical and Computational Study of Copper Histidine Complex via Cyclic Voltammetry
L-Histidine regulates body function and involve in the synthesis of hemoglobin, repairing of tissues and strengthens of immune system. In this study, Cyclic Voltammetry (CV) is used with 0.1 M Potassium Chloride as a supporting electrolyte to determine the accurate metal ligand ratio between Cu+2 and L-Histidine. In CV potential window is set between +0.6 to -0.4V to record theVoltammogram. Voltammograms were recorded by varying scan rate from 50mV/s to 300mV/s. Cyclic Voltammetry is used to analyzed the interfacial performance of the complex and repeated CyclicVoltammograms (07 cycles) were recorded at Glassy Carbon Electrode (GCE), that shows no change in peak current intensity of both anodic and cathodic peak. Further, neither pre nor any post peak was observed. These interpretation express that reactant and product are not involve in the adsorption-desorption process at the surface of Glassy Carbon Electrode (GCE). These remarks suggest that it is diffusion controlled process in the above mentioned system. The interaction of Cu+2 and L-Histidine were not reported before through Cyclic Voltammetry. Furthermore, in this study structure of Cu+2 vs. L-Histidine complex is investigated from a theoretical perspective. Optimization of Cu+2 vs. L-Histidine complex was carried out by DFT method and result verifies that stable structure of Cu+2 vs. L-Histidine complex exist as square planar structure in 1:2 ratio respectively. The computed structure has correlation with experimental results and Voltammogram of 1:2 ratio complex of Cu+2 vs. L-Histidine suggested that it exist in Square planar geometry.
期刊介绍:
This journal covers different research areas in the field of Chemistry. These include; Analytical Chemistry, Applied Chemistry, Biochemistry, Environmental Chemistry, Industrial Chemistry, Inorganic Chemistry, Organic Chemistry and Physical Chemistry. The journal publishes full length articles and Reviews from researchers in academia in addition to featuring comments. Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry.