D. Kannur, Srikrishna Nandanwadkar, Swapnil Dhawane, S. Phulambrikar, K. Khandelwal
{"title":"疏水草种子提取物抗胁迫活性的实验评价","authors":"D. Kannur, Srikrishna Nandanwadkar, Swapnil Dhawane, S. Phulambrikar, K. Khandelwal","doi":"10.4103/asl.ASL_191_17","DOIUrl":null,"url":null,"abstract":"Background: Stress is the causative factor for various diseases and disorders faced by majority of the diseased population. The seeds of Kokilākṣa Hygrophila schulli are attributed with Rasāyana properties as per the Ayurvedic literature. Considering the above, the seed extracts of H. schulli were screened for antistress activity in animals. Aim: To investigate the adaptogenic activity of ethanolic and hexane extracts of Hygrophila schulli seeds using in vivo models. Materials and Methods: The ethanolic and hexane extracts of Hygrophila schulli were subjected to qualitative chemical analysis to detect the presence of various phytoconstituents. The extracts were subjected HPLC analysis. The chromatographic analysis was carried out which revealed the multicomponent and complex nature of the extracts. The seed extracts of H. schulli were screened for antistress activity using Swim Endurance test in mice and Cold-Immobilization Stress model in rats to ascertain the Adaptogenic potential. Results: HPLC analysis confirmed the presence of flavonoid Quercetin, the ethanolic and hexane extracts were found to increase the swim endurance time, both extracts lowered the elevated blood glucose, cholesterol as well as triglyceride levels in cold immobilization stress model and maintained normal homeostasis. Conclusion: Hygrophila schulli enhances the physical endurance as well as normalizes the body imbalance due to stressors. The seeds of Hygrophila schulli thus possess adaptogenic property.","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"37 1","pages":"31 - 36"},"PeriodicalIF":0.0000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"8","resultStr":"{\"title\":\"Experimental evaluation of Hygrophila Schulli seed extracts for antistress activity\",\"authors\":\"D. Kannur, Srikrishna Nandanwadkar, Swapnil Dhawane, S. Phulambrikar, K. Khandelwal\",\"doi\":\"10.4103/asl.ASL_191_17\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Stress is the causative factor for various diseases and disorders faced by majority of the diseased population. The seeds of Kokilākṣa Hygrophila schulli are attributed with Rasāyana properties as per the Ayurvedic literature. Considering the above, the seed extracts of H. schulli were screened for antistress activity in animals. Aim: To investigate the adaptogenic activity of ethanolic and hexane extracts of Hygrophila schulli seeds using in vivo models. Materials and Methods: The ethanolic and hexane extracts of Hygrophila schulli were subjected to qualitative chemical analysis to detect the presence of various phytoconstituents. The extracts were subjected HPLC analysis. The chromatographic analysis was carried out which revealed the multicomponent and complex nature of the extracts. The seed extracts of H. schulli were screened for antistress activity using Swim Endurance test in mice and Cold-Immobilization Stress model in rats to ascertain the Adaptogenic potential. Results: HPLC analysis confirmed the presence of flavonoid Quercetin, the ethanolic and hexane extracts were found to increase the swim endurance time, both extracts lowered the elevated blood glucose, cholesterol as well as triglyceride levels in cold immobilization stress model and maintained normal homeostasis. Conclusion: Hygrophila schulli enhances the physical endurance as well as normalizes the body imbalance due to stressors. The seeds of Hygrophila schulli thus possess adaptogenic property.\",\"PeriodicalId\":7805,\"journal\":{\"name\":\"Ancient Science of Life\",\"volume\":\"37 1\",\"pages\":\"31 - 36\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ancient Science of Life\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/asl.ASL_191_17\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ancient Science of Life","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/asl.ASL_191_17","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Experimental evaluation of Hygrophila Schulli seed extracts for antistress activity
Background: Stress is the causative factor for various diseases and disorders faced by majority of the diseased population. The seeds of Kokilākṣa Hygrophila schulli are attributed with Rasāyana properties as per the Ayurvedic literature. Considering the above, the seed extracts of H. schulli were screened for antistress activity in animals. Aim: To investigate the adaptogenic activity of ethanolic and hexane extracts of Hygrophila schulli seeds using in vivo models. Materials and Methods: The ethanolic and hexane extracts of Hygrophila schulli were subjected to qualitative chemical analysis to detect the presence of various phytoconstituents. The extracts were subjected HPLC analysis. The chromatographic analysis was carried out which revealed the multicomponent and complex nature of the extracts. The seed extracts of H. schulli were screened for antistress activity using Swim Endurance test in mice and Cold-Immobilization Stress model in rats to ascertain the Adaptogenic potential. Results: HPLC analysis confirmed the presence of flavonoid Quercetin, the ethanolic and hexane extracts were found to increase the swim endurance time, both extracts lowered the elevated blood glucose, cholesterol as well as triglyceride levels in cold immobilization stress model and maintained normal homeostasis. Conclusion: Hygrophila schulli enhances the physical endurance as well as normalizes the body imbalance due to stressors. The seeds of Hygrophila schulli thus possess adaptogenic property.