尼日利亚东南部阿坝艾滋病毒感染者中丙型肝炎表面抗原血症的血清患病率

Q4 Medicine
A. Ngwogu, K. Ngwogu, P. Onyemachi
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引用次数: 0

摘要

背景:为了使尼日利亚的卫生机构有助于根除致命的丙型肝炎病毒(HCV)感染的传播,需要对所有新诊断的人类免疫缺陷病毒(HIV)患者进行常规筛查,就像对乙型肝炎病毒(HBV)所做的那样。这将使护理提供者和政策制定者认识到一种被忽视的疾病状况的负担,并在分配有限资源时知道重点放在哪里。目的:了解新诊断HIV患者HCV的血清阳性率。设计:以医院为基础的前瞻性研究。地点:尼日利亚东南部阿巴的阿比亚州立大学教学医院。对象:2016年3月1日至6月1日在该院HIV治疗单元新就诊的确诊HIV阳性成人患者306例。结果:研究期间306例新发HIV患者年龄6 ~ 70岁,平均36±10.2岁。艾滋病毒感染率最高的年龄段为30-39岁(38.20%),最低的年龄段为0-19岁(4.60%)。研究人群男性患病率为34.30%,男女比例为1:2。HCV患病率最高的年龄组为30 ~ 39岁(37.5%),低于20岁(0.05)。CD4计数大于350的HCV患病率为33.30%。结论:HCV感染在HIV感染者中较为常见。建议即使在资源有限的环境中,也应对所有HIV血清阳性个体进行HCV和HBV的常规筛查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Seroprevalence of hepatitis C surface antigenemia among HIV-infected individuals in Aba, South Eastern, Nigeria
Background: In order for health institutions in Nigeria to contribute towards the eradication of the spread of the deadly hepatitis C virus (HCV) infection, there is need for regular routine screening of all newly diagnosed human immunodeficiency virus (HIV) patients as is done for hepatitis B virus (HBV). This would enable care providers and policy makers appreciate the burden of an otherwise neglected disease condition and know where to focus as they distribute the limited resources.Objective: To evaluate the seroprevalence of HCV among newly diagnosed HIV patients.Design: A hospital based prospective study.Setting: The Abia State University Teaching Hospital (ABSUTH), Aba in South Eastern Nigeria.Subjects: Three hundred and six confirmed HIV positive adult patients who presented newly at the HIV treatment unit of the hospital between 1st March and 1st June 2016.Results: The age of the patients ranged from 6-70 years with a mean of 36±10.2 years among the 306 newly diagnosed HIV patients within the studied period. The highest prevalence of HIV infection was seen between the age ranges of 30-39 years (38.20%) while the lowest prevalence was seen between the age ranges of 0-19 years (4.60%). Male prevalence of the studied population was 34.30%, giving a male to female ratio of 1:2. Age group with highest prevalence of HCV (37.5%) was 30-39 years while patients aged less than twenty ( 0.05). Prevalence of HCV among the patients with a CD4 count greater than 350 was 33.30%.Conclusion: The study showed that HCV infection is relatively common in HIV –infected individuals. It is recommended that routine screening for HCV alongside HBV should be done for all HIV seropositive individuals even in resource limited settings.
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来源期刊
East African medical journal
East African medical journal Medicine-Medicine (all)
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期刊介绍: The East African Medical Journal is published every month. It is intended for publication of papers on original work and reviews of all aspects of medicine. Communications bearing on clinical and basic research on problems relevant to East Africa and other African countries will receive special attention. Papers submitted for publication are accepted only on the understanding they will not be published elsewhere without the permission of the Editor-in-Chief
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