多发圆筒状瘤伴免疫组织化学特征1例报告

N. Watanabe, K. Kawase, Chisato Tawada, K. Yoneda, K. Hirai, Ayumi Niwa, Takuji Tanaka
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引用次数: 2

摘要

筒状瘤是一种良性皮肤附属物肿瘤,起源于卵泡内的多能干细胞。多发性柱状瘤通常是布鲁克-斯皮格勒综合征的一个组成部分,或者是家族性柱状瘤病的唯一皮肤病变。我们在此报告一例罕见的累及躯干的多发性柱状瘤,没有布鲁克-斯皮格勒综合征的任何其他特征,也没有家族史支持家族性柱状瘤病的可能性。本文还报道了参与圆筒状瘤发生的CYLD和NF-κB在肿瘤中的免疫组织化学特征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Case Report of Multiple Cylindroma with Immunohistochemical Features
Cylindroma is a benign skin appendageal tumor arising from pluripotent stem cells in the follicle. Multiple cylindroma typically occurs as a component of Brooke-Spiegler syndrome or as the only skin lesion of familial cylindromatosis. We herein report an unusual case of multiple cylindroma involving the trunk without any other features of Brooke-Spiegler syndrome and no family history supporting the possibility of familial cylindromatosis. Immunohistochemical features of CYLD and NF-κB, which are involved in the pathogenesis of cylindroma, in the tumors are also presented.
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