Pretrigeminal神经痛

S. Jindal, A. Singla
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引用次数: 10

摘要

典型的三叉神经痛是指沿三叉神经分布的短暂电击样疼痛,文献记载较多,但关于三叉神经痛的文献却不多。由于三叉神经痛具有相似的特征,因此在鉴别诊断牙源性疼痛时应考虑三叉神经痛。Symonds是第一个在少数患者出现典型的阵发性疼痛之前注意到钝的、持续的和疼痛的人。米切尔将这种前驱疼痛称为“前三叉神经痛”。这种前体疼痛的临床特征包括钝的、持续的疼痛,咀嚼食物、饮用热饮和冷饮可引起或加重疼痛。这类患者给牙医的诊断带来了挑战,因为检查可能会发现没有龋齿、牙龈萎缩、鼻窦炎,而且非甾体抗炎药和阿片类药物等镇痛药也不能缓解这些症状。根管治疗和拔牙对此类患者也无效,因为即使在进行根管治疗或拔牙后,同一区域的疼痛仍然存在。因此,这些患者需要仔细的病史和详细的牙科和神经学检查,以避免误诊为牙科疾病。三叉神经痛的鉴别诊断包括牙髓源性牙痛、鼻窦炎、肌面疼痛功能障碍综合征(MPDS)、非典型面部疼痛、颞下颌关节紊乱和三叉神经痛。牙髓源性疼痛可通过仔细的牙科检查和口腔内x线片加以鉴别。鼻塞、脓性鼻分泌物、脸颊及副鼻窦压痛(PNS片)有助于上颌鼻窦炎引起的上颌前磨牙或磨牙区类似疼痛的诊断。颞下颌关节紊乱和MPDS表现为慢性口面部疼痛,随着下颌的运动而加重。咀嚼肌压痛、颞下颌关节咔嗒声、开口受限是MPDS的特征。非典型面部疼痛与心因性原因有关,患者主诉在明显正常的牙齿或颌骨出现局部不佳的悸动痛或烧灼感,除抗抑郁药外,对所有治疗方案的反应都很差。临床表现为短暂的电击样神经沿程疼痛,有触发区和触发因子的存在,有助于鉴别典型三叉神经痛和前三叉神经痛。治疗性诊断是通过几天小剂量卡马西平和巴氯芬来诊断这类病例的方法。卡马西平每日三次,剂量为100mg,足以缓解症状并确认诊断虽然这种情况的发生率很低,但牙医应该……
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Pretrigeminal neuralgia
Typical trigeminal neuralgia, brief electric shock like pain along distribution of trigeminal nerve, is well documented in literature but not much is available about pre trigeminal neuralgia. Pre-trigeminal neuralgia should be considered in the differential diagnosis of pain of dental origin because of its similar features.Symonds was the first person who noted dull, continuous and aching pain before the typical paroxysmal pain appeared in few patients. [1] Mitchell was the person to term this prodromal pain as " pre-trigeminal neuralgia. Clinical features of this prodromal pain includesdull, continuous aching pain that may be triggered or aggravated by chewing food, drinking hot and cold liquids. Such patients pose a diagnostic challenge for dentist as examination may reveal absence of caries, gingival recession, sinusitis and symptoms are not relieved with analgesics like NSAIDs and opioids. Root canal treatment and extraction are also of no use in such patients because painpersists in the same region even after performing root canal treatment or extraction. So a careful history and detailed dental and neurological examination is required in such patients to avoid misdiagnosis as dental disease. Differential diagnosis of pre trigeminal neuralgia includes dental pain of pulpal origin, sinusitis, myofacial pain dysfunction syndrome (MPDS), atypical facial pain, TMJ disorders and trigeminal neuralgia. Pain of pulpal origin can be differentiated with careful dental examination and intra oral radiographs. Presence of blocked nose, purulent nasal discharge, tenderness over cheek areas and paranasal sinus (PNS view) radiograph can help in diagnosis ofsimilar pain in maxillary premolar or molar region due to maxillary sinusitis. TMJ disorders and MPDS presents with chronic orofacial pain that aggravates with movement of jaws. Tenderness of muscles of mastication, clicking sound in TMJ and limited mouth opening are characteristic features of MPDS. Atypical facial pain is associated with psychogenic causesin which patient complains of poorly localized throbbing pain or burning sensation in apparently normal teeth or jaws that responds poorly to all treatment plans except antidepressants. Clinical presentation with brief electric shock like pain along the course of nerve, presence of triggering zones and triggering factors helps in differentiating typical trigeminal neuralgia from pre-trigeminal neuralgia. Therapeutic diagnosis is the method to diagnose such cases by giving small doses of carbamazepine and baclofen for few days. A dosage of 100mg of carbamazepinethrice dailywas found sufficient forrelief of symptoms and to confirm the diagnosis.5 Although incidence of such cases is very low but dentist should be …
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