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引用次数: 1
摘要
我们使用电感耦合等离子体发射光谱(ICP-OES)对牙形刺和岩石进行了分析，并采用统计方法比较了牙形刺和同期人体组织中砷和铅的临界点。我们发现古代海洋中含有高浓度的砷，这些砷也出现在牙形石牙齿中，并且是从岩石中浸出的;生物富集。我们发现，随着时间的推移，达到临界点的时间显著下降(P=0.01)，这意味着现代牙齿中这些神经毒性金属的来源已经减少，以至于铅和砷不再像在牙形石牙齿的磷灰石中那样在人类磷灰石中积累。随着As浓度的增加(P=0.01)和Pb浓度的增加(P=0.04)，超过临界点的概率显著增加。这表明这些金属的毒性作用可能是加性的。引用本文:Qualls C, Lucas SG, Ali AM, Appenzeller O(2018)临界点:人类与牙形刺的统计比较。[J]中国生物医学工程学报，9:393。doi: 10.4172 / 2155 - 6180.1000396
Tipping Points: A Statistical Comparison between Humans and Conodonts
We analyzed Conodonts and rocks using Inductively Coupled Plasma-Optical Emission Spectroscopy (ICP-OES) using statistical methods to compare the tipping points for arsenic (As) and lead (Pb) in conodonts and contemporaneous human tissues. We found that ancient seas contained high levels of As which also occurred in Conodont teeth and which was leached from rocks; a biogenic enrichment. We show that there is a significant decline in reaching the tipping point with time (P=0.01) implying that the sources of these neurotoxic metals in modern teeth have decreased such that Pb and As no longer accumulate in human apatite as it did in the apatite of Conodont teeth. The probability of exceeding the tipping point increases significantly with increasing As concentration (P=0.01) and increasing Pb concentration (P=0.04). This suggests that the toxic effects of these metals may be additive. Citation: Qualls C, Lucas SG, Ali AM, Appenzeller O (2018) Tipping Points: A Statistical Comparison between Humans and Conodonts. J Biom Biostat 9: 396. doi: 10.4172/2155-6180.1000396
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