三种预防脱敏膏的体外比较:非晶分析

A. Genovesi, S. Marconcini, M. Lelli, E. Giammarinaro, A. Barone, U. Covani
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引用次数: 1

摘要

背景与目的:牙本质过敏(DH)的特征是由于暴露的牙本质引起短暂的尖锐疼痛。如今,有大量的产品可以解决这个问题。本观察性研究的目的是比较三种预防性膏剂在体外牙本质小管闭塞中的疗效。方法:对10颗拔牙标本进行纵向中、远端切面。扫描电镜(SEM)形态学分析评估了三种不同预防糊剂在牙髓小管中的渗透:GSK的Nupro, Biorepair的Stomyprox,高露洁Pro-Sollievo。使用能量色散x射线分析(EDX探针)可以评估每种产品的确切成分。结果:扫描电镜分析表明,由于其结晶度较低,只有Biorepair的Stomyprox才能穿透牙本质小管。与其他两种颗粒较大的膏体相比,其小颗粒(≈1.60 μ)更适合小管管腔。小样本量和缺乏对小管填充的定量评价限制了这一结果。结论:牙本质小管闭塞治疗是减少牙本质过敏的有效方法之一。小颗粒更适合于小管的管腔。总之,选择结晶度低的预防糊剂是有生物学原理的。值得进一步研究的是,在临床环境中,由小颗粒羟基磷灰石制成的预防膏的效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
In Vitro Comparison of Three Desensitizing Prophylaxis Pastes: AMorphological Analysis
Background and Objective: Dentine hypersensitivity (DH) characterizes for short sharp pain arising from exposed dentine. Nowadays, there is a vast choice of products to overcome it. The aim of the present observational study was to compare the efficacy of three prophylaxis pastes in occluding dentinal tubules from in an in vitro setting. Methods: Longitudinal mesio-distal sections were obtained from a sample of ten extracted teeth. Morphological analysis with scanning electron microscopy (SEM) assessed the penetration of three different prophylaxis pastes in dentinal tubules: Nupro by GSK, Stomyprox by Biorepair, Colgate Pro-Sollievo. The use of the Energy Dispersive X-ray Analysis (EDX probe) allowed assessing the exact composition of each product. Results: The SEM analysis revealed that only Stomyprox by Biorepair could penetrate the dentinal tubule due to its low crystallinity. Its small sized particles (˜1.60 μ) fit better the tubules lumen if compared to the other two pastes with higher sized granules. The small sample size and the lacking of a quantitative evaluation of tubules filling limit this result. Conclusion: The occlusion of dentinal tubules is one of the possible ways to reduce dentine hypersensitivity in a professional setting. Small sized particles fit better the lumen of tubules. In conclusion, there is a biological rationale in preferring prophylaxis pastes characterized by a low crystallinity. It is worthy to investigate furthermore, and in a clinical setting, the efficacy of the prophylaxis paste made by small sized particles of Hydroxyapatite.
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