龈沟血在牙科诊所评估血糖水平的诊断效能:一项横断面研究

D. Patil, D. Kamalakkannan
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引用次数: 8

摘要

目的:在常规牙周探诊中获得的龈沟血(GCB)可能是血糖测量的来源。本研究的目的是比较牙龈沟血和手指刺血糖测量使用血糖仪与传统的实验室方法。材料与方法:研究组分为三组。第一组选择牙周炎伴探诊阳性出血患者30例。使用葡萄糖自我监测装置对两个部位的血液样本进行口腔内分析。第二组和第三组分别为50名糖尿病患者和50名非糖尿病患者。检测空腹血糖(FPG)后,采用同一设备分析空腹龈沟血(GCBG)和空腹毛细血管指血(CFBG)样品中的血糖水平。结果:龈沟血糖水平与毛细血管指棒血糖水平有显著相关(r= 0.93, p<0.001)。糖尿病患者和正常人群空腹龈沟血糖水平与空腹血糖之间存在相当大的相关性(r=0.75, p<0.001)。结论:常规牙周探诊血可用于血糖水平的测定。GCB可作为血糖仪测血糖的标记物。所描述的技术是安全的,易于执行,并有助于增加糖尿病筛查在牙科诊所的频率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diagnostic Efficacy of Gingival Crevicular Blood for Assessment of BloodGlucose Levels in Dental Office: A cross Sectional Study
Objectives: The gingival crevicular blood (GCB) obtained during routine periodontal probing may be a source for blood glucose measurements. The aim of this study was to compare gingival crevicular blood and fingerstick blood glucose measurements using a glucometer against the conventional laboratory methods. Materials and Methods: The study group comprised of three groups. In the first group 30 patients with periodontitis and positive bleeding on probing were chosen. Blood samples of two sites intraorally were analyzed using a glucose self-monitoring device. The second and third group comprised of 50 diabetic and 50 non-diabetic patients. After testing fasting plasma glucose (FPG), fasting glucose levels in gingival crevicular blood (GCBG), and fasting capillary fingerstick blood (CFBG) samples were analyzed using same device. Results: Significant correlation (r= 0.93, p<0.001) was found between gingival crevicular blood glucose levels and capillary finger stick blood glucose levels. Considerable correlation (r=0.75, p<0.001) was found between levels of fasting gingival crevicular blood glucose and fasting blood glucose both in diabetic patients and the normal population. Conclusion: It is evident that the blood obtained during routine periodontal probing can be used for estimation of blood glucose levels. GCB can be used as a marker for blood glucose estimation using glucometer. The technique described is safe, easy to perform and helps to increase the frequency of diabetes screening in dental office.
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