白血病和电离辐射再谈

J. Cuttler, J. Welsh
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引用次数: 22

摘要

20世纪50年代末,为了阻止原子弹试验和阻止核能的发展,一场世界性的辐射健康恐慌产生了。尽管有大量证据与癌症预测相矛盾,但这种恐惧仍在继续。它损害了在医学诊断成像和放射治疗中使用低辐射剂量。这篇简短的文章回顾了两项重要研究中的第二项,这一研究彻底改变了辐射防护,并指出了一个被忽视的严重错误。在分析广岛和长崎受辐射人群中19.5万名幸存者的白血病发病率时,这一错误使使用LNT模型评估电离辐射致癌风险的方法无效。根据约96,800人的数据,辐射诱发白血病的急性阈值剂量约为50雷姆,即0.5西沃特。我们有理由认为,其他类型癌症的阈值高于这个水平。在有科学证据支持LNT假说之前,不应预测或暗示低于该值的急性暴露会导致过度癌症风险(或任何其他健康风险)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Leukemia and Ionizing Radiation Revisited
A world-wide radiation health scare was created in the late 1950s to stop the testing of atomic bombs and block the development of nuclear energy. In spite of the large amount of evidence that contradicts the cancer predictions, this fear continues. It impairs the use of low radiation doses in medical diagnostic imaging and radiation therapy. This brief article revisits the second of two key studies, which revolutionized radiation protection, and identifies a serious error that was missed. This error in analyzing the leukemia incidence among the 195,000 survivors, in the combined exposed populations of Hiroshima and Nagasaki, invalidates use of the LNT model for assessing the risk of cancer from ionizing radiation. The threshold acute dose for radiation-induced leukemia, based on about 96,800 humans, is identified to be about 50 rem, or 0.5 Sv. It is reasonable to expect that the thresholds for other cancer types are higher than this level. No predictions or hints of excess cancer risk (or any other health risk) should be made for an acute exposure below this value until there is scientific evidence to support the LNT hypothesis.
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