Advances in laser speckle flowgraphy technique

Laser Speckle Flowgraphy(LSFG),a full field optical imaging method without scanning in biomedical field,has become a novel technique for monitoring dynamic fluctuation of blood flow owning to its outstanding features. Its validity has been demonstrated by many clinical instances in the recent twenty years.Research to date on the LSFG has led to improvements in the theory and diversity of systems.The development and the basic theory of LSFG is introduced systematically,and state-of-the-art of study on theory and system design are reviewed and illustrated by reference to recent publications.The model of velocity distribution,the algorithm of contrast analysis,the match of the size of speckle and the pixel,and the exposure time are discussed in detail.