一罕见的转移性脊髓压迫源自角外纵隔卵黄囊肿瘤:1例报告

Ma Jeasa G. Torrefranca, Rainick T. Navarro, C. Go
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引用次数: 0

摘要

摘要非半精瘤性生殖细胞肿瘤(NSGCT)发生在肛门外的脊髓转移是一种罕见的事件,在最初的表现更是不常见。在这个病例报告中,我们提出了一个20岁男性脊髓压迫的临床表现。他表现为截瘫、神经性膀胱和肠功能障碍。脊髓磁共振成像(MRI)显示第9胸椎转移,脊髓压迫伴水肿。胸部计算机断层扫描进一步显示纵隔和右侧下腔肿块。其组织病理学特征与卵黄囊瘤(YST)一致。进一步的骨显像检查显示脊柱转移。本病例为一罕见的临床表现和疾病表现,是一种起源于纵隔并引起脊髓压迫的转移性输卵管外囊肿。尽管这种情况很少见,但鉴于NSGCT的转移率及其相关的不良预后,脊髓压迫应提高对转移性病变的认识并及时评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Rare Case of Metastatic Spinal Cord Compression Originating from Extragonadal Mediastinal Yolk Sac Tumor: A Case Report
Spinal metastases of nonseminomatous germ cell tumor (NSGCT) found in extragonadal location is a rare event and even more uncommon at the initial presentation. In this case report, we present a 20-year old male’s clinical presentation of spinal cord compression. He presented with paraplegia, neurologic bladder, and bowel dysfunction. Spinal Magnetic Resonance Imaging (MRI) demonstrated 9th thoracic vertebra metastasis, and cord compression with edema. A chest computed tomography scan with contrast further revealed mediastinal and right infrahilar mass. Its histopathological features were consistent with Yolk Sac Tumor (YST). Further investigation using bone scintigraphy revealed spinal metastasis. This case represents a rare clinical presentation and disease manifestation of a metastatic extragonadal YST originating from the mediastinum and causing spinal cord compression in an adult male. Although it is rare, spinal cord compression should raise awareness and prompt evaluation for metastatic lesions given the rate of NSGCT metastasis and its associated poor prognosis.
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