{"title":"咽部弥漫性大b细胞淋巴瘤临床病理特点分析","authors":"Chenghong Zheng","doi":"10.3760/CMA.J.ISSN1673-8799.2010.12.34","DOIUrl":null,"url":null,"abstract":"Objective To investigate the clinicopathology characteristics of asopharyngeal diffuse large B-cell lymphoma(DLBCL) and improve diagnosis of the disease. Methods The clinical, immunophenotypic and histopathologic features of 12 cases asopharyngeal DLBCL were retrospectively studied. The expression of CD20, CD3, CD10, BCL6, MUM-1, Ki-67, CD30, AE1/3, CD30, ALK, CD5and CyclinD1 was detected. Results All patients were primary DLBCL. Among the 12 patients,8 were males and 4 were femals. The age ranged from 34 to 67 years, average age 48 years old. Among them,7 cases were germinal centre B-cell-like(GCB) , 5cases were non-germinal centre B-cell-like(non-GCB). Conclusion Asopharyngeal DLBCLs are easily misdiagnosed as carcinomas. The correct diagnosis of DLBCL may be reached by combination of clinic, histological and immunological features. \n \nKey words: \nLymphoma nasopharyngeal; Pathology; Diagnosis differential","PeriodicalId":64135,"journal":{"name":"中国临床实用医学","volume":"4 1","pages":"65-66"},"PeriodicalIF":0.0000,"publicationDate":"2010-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Analysis on the clinicopathology characteristics of diffuse large B-cell lymphoma in asopharyngeal\",\"authors\":\"Chenghong Zheng\",\"doi\":\"10.3760/CMA.J.ISSN1673-8799.2010.12.34\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective To investigate the clinicopathology characteristics of asopharyngeal diffuse large B-cell lymphoma(DLBCL) and improve diagnosis of the disease. Methods The clinical, immunophenotypic and histopathologic features of 12 cases asopharyngeal DLBCL were retrospectively studied. The expression of CD20, CD3, CD10, BCL6, MUM-1, Ki-67, CD30, AE1/3, CD30, ALK, CD5and CyclinD1 was detected. Results All patients were primary DLBCL. Among the 12 patients,8 were males and 4 were femals. The age ranged from 34 to 67 years, average age 48 years old. Among them,7 cases were germinal centre B-cell-like(GCB) , 5cases were non-germinal centre B-cell-like(non-GCB). Conclusion Asopharyngeal DLBCLs are easily misdiagnosed as carcinomas. The correct diagnosis of DLBCL may be reached by combination of clinic, histological and immunological features. \\n \\nKey words: \\nLymphoma nasopharyngeal; Pathology; Diagnosis differential\",\"PeriodicalId\":64135,\"journal\":{\"name\":\"中国临床实用医学\",\"volume\":\"4 1\",\"pages\":\"65-66\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-12-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中国临床实用医学\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN1673-8799.2010.12.34\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国临床实用医学","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN1673-8799.2010.12.34","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Analysis on the clinicopathology characteristics of diffuse large B-cell lymphoma in asopharyngeal
Objective To investigate the clinicopathology characteristics of asopharyngeal diffuse large B-cell lymphoma(DLBCL) and improve diagnosis of the disease. Methods The clinical, immunophenotypic and histopathologic features of 12 cases asopharyngeal DLBCL were retrospectively studied. The expression of CD20, CD3, CD10, BCL6, MUM-1, Ki-67, CD30, AE1/3, CD30, ALK, CD5and CyclinD1 was detected. Results All patients were primary DLBCL. Among the 12 patients,8 were males and 4 were femals. The age ranged from 34 to 67 years, average age 48 years old. Among them,7 cases were germinal centre B-cell-like(GCB) , 5cases were non-germinal centre B-cell-like(non-GCB). Conclusion Asopharyngeal DLBCLs are easily misdiagnosed as carcinomas. The correct diagnosis of DLBCL may be reached by combination of clinic, histological and immunological features.
Key words:
Lymphoma nasopharyngeal; Pathology; Diagnosis differential
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
