{"title":"了解动态:探讨肠道健康和饮食干预对类风湿关节炎炎症生物标志物的影响","authors":"A. Srivastava","doi":"10.35248/2161-0665.11.5.380","DOIUrl":null,"url":null,"abstract":"It Rheumatoid arthritis (RA) is a debilitating and disabling autoimmune disorder characterized by joint pain, stiffness and lost muscle function. About 1% of population accounts for individuals suffering from this disease and 30% of RA patients find it difficult to perform daily task in a span of next 10 years of the onset of the condition. Moreover, it is observed that women are more affected than men between the ages of 40-70 years; children are also affected at any age. It causes painful inflammation and subsequent cartilage and bone destruction owing to pro inflammatory triggers like IL-6, cytokines, TNF-α with no clear signs in the starting. Current drug treatment for treating rheumatoid arthritis is expensive and deleterious on overall health on long-term use. Gut abnormalities can be an underlying cause of disease activity in RA. RA in a pre-disposed condition starts in the gut and may run in the families.","PeriodicalId":91373,"journal":{"name":"Pediatrics & therapeutics : current research","volume":"11 1","pages":"1-3"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Understanding Dynamics: Probing into Gut Health and DietaryInterventions on Biomarkers of Inflammation in Rheumatoid Arthritis\",\"authors\":\"A. Srivastava\",\"doi\":\"10.35248/2161-0665.11.5.380\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"It Rheumatoid arthritis (RA) is a debilitating and disabling autoimmune disorder characterized by joint pain, stiffness and lost muscle function. About 1% of population accounts for individuals suffering from this disease and 30% of RA patients find it difficult to perform daily task in a span of next 10 years of the onset of the condition. Moreover, it is observed that women are more affected than men between the ages of 40-70 years; children are also affected at any age. It causes painful inflammation and subsequent cartilage and bone destruction owing to pro inflammatory triggers like IL-6, cytokines, TNF-α with no clear signs in the starting. Current drug treatment for treating rheumatoid arthritis is expensive and deleterious on overall health on long-term use. Gut abnormalities can be an underlying cause of disease activity in RA. RA in a pre-disposed condition starts in the gut and may run in the families.\",\"PeriodicalId\":91373,\"journal\":{\"name\":\"Pediatrics & therapeutics : current research\",\"volume\":\"11 1\",\"pages\":\"1-3\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pediatrics & therapeutics : current research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.35248/2161-0665.11.5.380\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatrics & therapeutics : current research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.35248/2161-0665.11.5.380","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Understanding Dynamics: Probing into Gut Health and DietaryInterventions on Biomarkers of Inflammation in Rheumatoid Arthritis
It Rheumatoid arthritis (RA) is a debilitating and disabling autoimmune disorder characterized by joint pain, stiffness and lost muscle function. About 1% of population accounts for individuals suffering from this disease and 30% of RA patients find it difficult to perform daily task in a span of next 10 years of the onset of the condition. Moreover, it is observed that women are more affected than men between the ages of 40-70 years; children are also affected at any age. It causes painful inflammation and subsequent cartilage and bone destruction owing to pro inflammatory triggers like IL-6, cytokines, TNF-α with no clear signs in the starting. Current drug treatment for treating rheumatoid arthritis is expensive and deleterious on overall health on long-term use. Gut abnormalities can be an underlying cause of disease activity in RA. RA in a pre-disposed condition starts in the gut and may run in the families.