{"title":"LOX-1在预测急性脑卒中预后中的作用","authors":"Su Pu, Hui Zheng, Hui Wang, Fang Wang, Shunjun Li, Yueyu Tang","doi":"10.3760/CMA.J.ISSN.1673-8799.2016.03.007","DOIUrl":null,"url":null,"abstract":"Objective \nThe aim of this study is to inquire awareness of predictive value of LOX-1 to acute stroke patients. \n \n \nMethods \n60 cases of acute stroke patients, including 49 patients with Ischemic stroke and 11 patients with hemorrhagic apoplexy, 30 healthy persons were selected as control group. Respectively, in patients with the third day, the 14th day, the 90th day, collecting blood of elbow vein, measuring the serum levels of LOX-1 by enzyme-linked immunosorbent assay, marking NIHSS score simultaneously. We analysed the relationship between LOX-1 level and NIHSS score , the size of this relationship. \n \n \nResults \nSerum LOX-1 concentrations of third day, 14th day and 90th day in the case group were compared with the control group. The result is that serum LOX-1 level in the case group were apparently higher than that of the control group, the difference was statistically significant(P<0.05); The D-value of 14th days and third days NIHSS score was positively correlated with the change of LOX-1 concentration(γ=0.780, P=0.000), the D-value of 90th days and third days NIHSS score was positively correlated with the change of LOX-1 concentration(γ=0.378, P=0.003). \n \n \nConclusion \nLOX-1 is a biochemical indicator which can predict the prognosis of patients with acute stroke. \n \n \nKey words: \nLOX-1; Stroke; Prognosis","PeriodicalId":64135,"journal":{"name":"中国临床实用医学","volume":"7 1","pages":"20-23"},"PeriodicalIF":0.0000,"publicationDate":"2016-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The effect of LOX-1 in predicting the prognosis of acute stroke\",\"authors\":\"Su Pu, Hui Zheng, Hui Wang, Fang Wang, Shunjun Li, Yueyu Tang\",\"doi\":\"10.3760/CMA.J.ISSN.1673-8799.2016.03.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective \\nThe aim of this study is to inquire awareness of predictive value of LOX-1 to acute stroke patients. \\n \\n \\nMethods \\n60 cases of acute stroke patients, including 49 patients with Ischemic stroke and 11 patients with hemorrhagic apoplexy, 30 healthy persons were selected as control group. Respectively, in patients with the third day, the 14th day, the 90th day, collecting blood of elbow vein, measuring the serum levels of LOX-1 by enzyme-linked immunosorbent assay, marking NIHSS score simultaneously. We analysed the relationship between LOX-1 level and NIHSS score , the size of this relationship. \\n \\n \\nResults \\nSerum LOX-1 concentrations of third day, 14th day and 90th day in the case group were compared with the control group. The result is that serum LOX-1 level in the case group were apparently higher than that of the control group, the difference was statistically significant(P<0.05); The D-value of 14th days and third days NIHSS score was positively correlated with the change of LOX-1 concentration(γ=0.780, P=0.000), the D-value of 90th days and third days NIHSS score was positively correlated with the change of LOX-1 concentration(γ=0.378, P=0.003). \\n \\n \\nConclusion \\nLOX-1 is a biochemical indicator which can predict the prognosis of patients with acute stroke. \\n \\n \\nKey words: \\nLOX-1; Stroke; Prognosis\",\"PeriodicalId\":64135,\"journal\":{\"name\":\"中国临床实用医学\",\"volume\":\"7 1\",\"pages\":\"20-23\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-06-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中国临床实用医学\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN.1673-8799.2016.03.007\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国临床实用医学","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1673-8799.2016.03.007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The effect of LOX-1 in predicting the prognosis of acute stroke
Objective
The aim of this study is to inquire awareness of predictive value of LOX-1 to acute stroke patients.
Methods
60 cases of acute stroke patients, including 49 patients with Ischemic stroke and 11 patients with hemorrhagic apoplexy, 30 healthy persons were selected as control group. Respectively, in patients with the third day, the 14th day, the 90th day, collecting blood of elbow vein, measuring the serum levels of LOX-1 by enzyme-linked immunosorbent assay, marking NIHSS score simultaneously. We analysed the relationship between LOX-1 level and NIHSS score , the size of this relationship.
Results
Serum LOX-1 concentrations of third day, 14th day and 90th day in the case group were compared with the control group. The result is that serum LOX-1 level in the case group were apparently higher than that of the control group, the difference was statistically significant(P<0.05); The D-value of 14th days and third days NIHSS score was positively correlated with the change of LOX-1 concentration(γ=0.780, P=0.000), the D-value of 90th days and third days NIHSS score was positively correlated with the change of LOX-1 concentration(γ=0.378, P=0.003).
Conclusion
LOX-1 is a biochemical indicator which can predict the prognosis of patients with acute stroke.
Key words:
LOX-1; Stroke; Prognosis
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