梅山猪不同发育阶段各组织中m6a相关基因的表达分析

IF 1 4区农林科学 Q3 Agricultural and Biological Sciences

Revista Brasileira De Zootecnia-Brazilian Journal of Animal Science Pub Date : 2023-04-17 DOI:10.37496/rbz5220210149

Yanan Cao, Shuoshuo Zhang, Guangzheng Wang, Shuai Zhang, Wen-hua Bao, Shenglong Wu

{"title":"梅山猪不同发育阶段各组织中m6a相关基因的表达分析","authors":"Yanan Cao, Shuoshuo Zhang, Guangzheng Wang, Shuai Zhang, Wen-hua Bao, Shenglong Wu","doi":"10.37496/rbz5220210149","DOIUrl":null,"url":null,"abstract":"- To characterize the N6-methyladenosine (m 6 A)-related gene expression profiles in various tissues of Meishan pigs at different stages, m 6 A modification-related genes ( METTL3 , METTL14 , METTL16 , WTAP , RBM15 , and FTO ) were detected from newborn to physical maturity of Meishan pigs at eight important developmental stages (1, 7, 14, 21, 28, 35, 134, and 158 days old). The expression of m 6 A-related genes was tissue-specific. Furthermore, the level of METTL3 messenger RNA (mRNA) was higher on day 35 than in other stages in most tissues, and the expression of METTL14 increased after day 35, and FTO exhibited a peak on day 14 in muscle, intestine, lymph nodes, thymus, and kidney. This study provided a reference for an in-depth study of the expression patterns of m 6 A modification-related genes in Meishan pigs.","PeriodicalId":49614,"journal":{"name":"Revista Brasileira De Zootecnia-Brazilian Journal of Animal Science","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Expression analysis of m6A-related genes in various tissues of Meishan pigs at different developmental stages\",\"authors\":\"Yanan Cao, Shuoshuo Zhang, Guangzheng Wang, Shuai Zhang, Wen-hua Bao, Shenglong Wu\",\"doi\":\"10.37496/rbz5220210149\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"- To characterize the N6-methyladenosine (m 6 A)-related gene expression profiles in various tissues of Meishan pigs at different stages, m 6 A modification-related genes ( METTL3 , METTL14 , METTL16 , WTAP , RBM15 , and FTO ) were detected from newborn to physical maturity of Meishan pigs at eight important developmental stages (1, 7, 14, 21, 28, 35, 134, and 158 days old). The expression of m 6 A-related genes was tissue-specific. Furthermore, the level of METTL3 messenger RNA (mRNA) was higher on day 35 than in other stages in most tissues, and the expression of METTL14 increased after day 35, and FTO exhibited a peak on day 14 in muscle, intestine, lymph nodes, thymus, and kidney. This study provided a reference for an in-depth study of the expression patterns of m 6 A modification-related genes in Meishan pigs.\",\"PeriodicalId\":49614,\"journal\":{\"name\":\"Revista Brasileira De Zootecnia-Brazilian Journal of Animal Science\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2023-04-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Brasileira De Zootecnia-Brazilian Journal of Animal Science\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.37496/rbz5220210149\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Agricultural and Biological Sciences\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Brasileira De Zootecnia-Brazilian Journal of Animal Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.37496/rbz5220210149","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Agricultural and Biological Sciences","Score":null,"Total":0}

引用次数: 0

摘要

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Expression analysis of m6A-related genes in various tissues of Meishan pigs at different developmental stages

- To characterize the N6-methyladenosine (m 6 A)-related gene expression profiles in various tissues of Meishan pigs at different stages, m 6 A modification-related genes ( METTL3 , METTL14 , METTL16 , WTAP , RBM15 , and FTO ) were detected from newborn to physical maturity of Meishan pigs at eight important developmental stages (1, 7, 14, 21, 28, 35, 134, and 158 days old). The expression of m 6 A-related genes was tissue-specific. Furthermore, the level of METTL3 messenger RNA (mRNA) was higher on day 35 than in other stages in most tissues, and the expression of METTL14 increased after day 35, and FTO exhibited a peak on day 14 in muscle, intestine, lymph nodes, thymus, and kidney. This study provided a reference for an in-depth study of the expression patterns of m 6 A modification-related genes in Meishan pigs.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Revista Brasileira De Zootecnia-Brazilian Journal of Animal Science 农林科学-奶制品与动物科学

CiteScore

1.90

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： The Revista Brasileira de Zootecnia (RBZ; Brazilian Journal of Animal Science) encompasses all fields of Animal Science Research. The RBZ publishes original scientific articles in the areas of Aquaculture, Biometeorology and Animal Welfare, Forage Crops and Grasslands, Animal and Forage Plants Breeding and Genetics, Animal Reproduction, Ruminant and Non-Ruminant Nutrition, and Animal Production Systems and Agribusiness.