Illnesses of Unknown Etiology.

A public health event (PHE) is defined as any occurrence that may have negative consequences for human health, including those that have not yet caused disease or illness but that have potential and those that may require a coordinated response . This framework focuses on PHEs of initially unknown etiology, which are PHEs for which the cause has not yet been determined. For such events, the One Health approach is recommended, where the ministry of health works in close collaboration with other ministries and multisectoral partners to enhance teamwork and improve efficiencies in preparedness, response, and monitoring and evaluation (M&E).