自然杀伤细胞

Ryumachi. [Rheumatism] Pub Date : 2020-02-02 DOI:10.32388/7h1clk

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引用次数: 16

摘要

NK细胞可以预防多种癌症和感染。NK细胞在骨髓中发育，约占外周循环和次级淋巴器官淋巴细胞总数的510%。NK细胞的效应功能包括直接的自然细胞毒性，抗体依赖性细胞细胞毒性(ADCC)，以及间接调节其他免疫细胞功能的炎症细胞因子和趋化因子的分泌。NK细胞在骨髓中发育[1]NK细胞在抗病毒免疫中的重要性首次被发现，先天性NK细胞缺乏的患者有压倒性的病毒感染bbb

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Natural Killer Cell

NK cells protect against a variety of cancers and infection. NK cells develop in the bone marrow and constitute about 510% of total lymphocytes in the peripheral circulation and secondary lymphoidal or-gans. Effector functions of NK cells include direct natural cytotoxicity, antibody-dependent cellular cy-totoxicity (ADCC), as well as secretion of inflammatory cytokines and chemokines that indirectly regulate the functions of other immune cells .NK cell development occurs in the bone marrow [1] importance of NK cells in anti-viral immunity was first demonstrated by the discovery that patients with a congenital deficiency of NK cells have overwhelming viral infections [2]

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Ryumachi. [Rheumatism]

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