粪便菌群移植作为复发性艰难梭菌相关性腹泻患者的治疗选择

Q4 Medicine
E. A. Ortenberg
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引用次数: 0

摘要

本文回顾了2017年至2022年期间最大的关于使用粪便微生物群移植(FMT)治疗复发性艰难梭菌相关性腹泻(CDAD)患者的研究,包括假膜性结肠炎。重点介绍了粪便菌群制剂的制备方法和给药方法。最近的系统综述和荟萃分析一致认为TFM是复发性CDAD的有效治疗选择。不同的粪便微生物群制备和给药方法(新鲜、冷冻、冻干)显示出相似的效果,但使用的方便性不同。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fecal microbiota transplantation as a treatment option for patients with recurrent Clostridioides difficile-associated diarrhea
This paper provides a review of the largest studies (over the period of 2017 to 2022) on the use of fecal microbiota transplantation (FMT) for the treatment of patients with recurrent *Clostridioides difficile*associated diarrhea (CDAD), including pseudomembranous colitis. A focus was made on methods of preparation and administration of fecal microbiota product. The recent systematic reviews and metaanalyses consistently consider TFM as an effective treatment option for recurrent CDAD. The different methods of fecal microbiota preparation and administration (fresh, frozen, lyophilized) show similar efficacy but differ by convenience of use.
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来源期刊
CiteScore
0.90
自引率
0.00%
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0
审稿时长
8 weeks
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