多灶性脊柱转移-早期手术治疗结果

P. Szczerba
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引用次数: 0

摘要

介绍。癌症患者数量不断增加。肿瘤学的重大发展和新治疗方法的引入,明确地延长了癌症患者的预期寿命,但代价是越来越多地暴露出晚期并发症。的目标。介绍Brzozow骨科肿瘤医院脊柱转移多部位治疗的方法、问题和早期结果。材料和方法。本科2010年至2016年共收治因脊柱转移的患者541例。术前计划包括Karnofsky生活质量评分、疼痛VAS评分和Frankel评分是否存在神经功能缺陷。541例的形态学转移根据病灶数量和位置进行分类。根据选择的入路对手术治疗进行评分。结果。在411例接受手术的患者中,获得疼痛减轻VAS评分。91例患者中有23例获得临床改善。305例患者的生活质量在Karnofskyego量表中得到改善。在80例非活动患者中,18例患者的神经功能得到改善,使其能够重新站立和行走。并发症以浅表和深部感染为主,共28例,其中21例需要手术治疗。23例因病情进展再次手术。9例患者疼痛明显加重,神经功能减退。术后2例死亡。术中大出血14例。植入物失稳2例。结论。脊柱转移多为多灶性转移。手术治疗转移到脊柱是一种有价值的治疗方法,明显提高了患者的生活质量。手术并发症是常见的,因为所有癌症患者的手术风险明显增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Multifocal spine methastasis – early surgical treatment results
Introduction. Constantly increasing number of patients with cancer. The significant development of oncology and the introduction of new treatments al- lowed explicitly extend the life expectancy of cancer patients at the cost of increasingly revealing the late complications. Aim. Presentation of methods, problems and early results of multi-site treatment of spinal metastases in the Department of Orthopaedic Oncology Hospital in Brzozow. Materials and methods. In the Department from 2010 to 2016 due to spinal metastases were treated 541 patients. Preoperative planning included quality of life in Karnofsky scale assesment, pain VAS scale and the presence of neurological deficits in Frankel scale. Morphology metastases of all 541 were classified due to numbers of lesions and location. Surgical treatment was rated due to chosen approach. Results. In 411 patients who underwent surgery, a reduction of pain VAS scale was obtained. From the 91 patients with paresis in 23 patients achieved clinical improvement. Quality of life assessed on a scale Karnofskyego increased in 305 patients. In the group of 80 non-ambulatory patients 18 patients improvement of neurological re-enabled vertical position and walking. Among the complications dominated by superficial and deep infections, which involved 28 patients, of which required surgical intervention in 21 patients. Further re-operated due to disease progression were 23 patients. Marked increase in pain and progression of neurological deficits were observed in 9 patients. In the postoperative period 2 patients died. 14 patients had heavy bleeding during the operation. Implants destabilization involved 2 patients. Conclusions. Metastasis in the spine are mostly multifocal. Surgical treatment of metastases to the spine is a valuable method of treatment, clearly improves the quality of life of patients. Complications of surgery are common and due to the clearly increased risk of surgery in all patients with cancer.
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