Evaluation of Ribonuclease (RNAse) Activity in the Sera of Women with Breast Tumor.

In this study 125 patients with breast tumors (61 patients with benign breast tumors, 64 patients with malignant breast tumors) with age range between (20-75) years collected from Center of Early Detection of Breast Cancer in Azady Teaching Hospital in Kirkuk City from November 2016 to end of May 2018 and matched with 50 healthy women as control group. Serum RNAse activity and total protein (albumin, globulin) concentration were estimated in all patients (benign and malignant) and compared to control group. The present observational study has shown a significant elevation in serum RNAase activity in cases of breast carcinoma and benign breast lesions as compared to control, which can use RNAse as tumor marker for breast tumor.