空心材料在新冠肺炎诊断中的应用进展

Abid Hussain, Sonia Shabbir, M. Faizan, Muhammad Ali Tajwar
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引用次数: 0

摘要

新冠肺炎疫情在中国武汉爆发以来,极大地改变了全球地缘政治、经济乃至社会标准规范。目前的世界格局在商业、旅游和教育方面发生了变化。冠状病毒的快速全球传播和高死亡率是药物开发人员面临的最大挑战。它将在纳米技术的帮助下,朝着识别和治疗新出现的冠状病毒的方向前进。新冠肺炎大流行引发了研究人员在短时间内应对这种困境的能力的问题。在本文中,我们描述了如何将空心材料开发为具有良好治疗效果的前药。探索新型冠状病毒抗病毒或诊断试剂的中空纳米颗粒。空心纳米材料在疫苗开发中至关重要,因为空心纳米复合材料适用于模拟病毒结构和抗原递送。一种从换能器产生信号的生物传感器,用于比较和分析诸如细胞受体、抗体、RNA、DNA和核酸等生物偶联物。不同的生物传感器,如石墨烯生物传感器、纳米等离子体传感器芯片、纳米材料生物传感器、电化学生物传感器、双模态生物传感器和光学生物传感器,具有许多优点和特点,应用范围广泛,最显著的是在医疗和监测诊断中。本文综述了智能和创新的生物/纳米材料和基质的现代实验研究,用于开发靶向和受控的药物释放系统、纳米传感器和纳米疫苗来对抗致病性病毒。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Progress of hollow materials in diagnosis of COVID-19
Since the outbreak of COVID-19 in Wuhan, China, it has dramatically changed the global geopolitics, economics, and even society standard norms. The present world scenario is changed regarding business, traveling, and education. Rapid global dissemination and the high mortality rate of coronaviruses are the greatest challenges for drug developers. It will be moving forward toward the identification and treatment of emerging coronaviruses with the aid of nanotechnology. The COVID-19 pandemic raised the question of researchers’ capability to manage this dilemma in a short period. In the present review, we described how hallow material could be developed as a pro-drug that shows an excellent therapeutic effect. Hollow nanoparticles that exploration of antiviral or diagnostic agents against emerging coronaviruses. Hollow nanomaterials in vaccine development are essential because hollow nanocomposites are suitable for mimicking viral structures and antigen delivery. A biosensor that generates a signal from a transducer for comparing and analyzing biological conjugates such as cell receptors, antibodies, RNA, DNA, and nucleic acids. Different biosensors, such as graphene-based biosensors, nanoplasmonic sensor chips, nanomaterial biosensors, electrochemical biosensors, dual modality biosensors, and optical biosensors, have several advantages, characteristics, and a wide range of applications, most remarkably in medical treatment and are used for monitoring and diagnosis. This review focuses on modern experimental studies to identify intelligent and innovative bio/nanomaterials and matrices for developing targeted and controlled drug release systems, nanosensors and nanovaccines to combat pathogenic viruses.
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