应用光动力疗法改善静脉源性营养溃疡患者的生活质量

T. Kharchenko, O. Melekhovets, Iuirii V. Melekhovets, A. Radko
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引用次数: 0

摘要

目的。目的分析光动力疗法治疗下肢营养性静脉溃疡后患者的生活质量动态变化。材料和方法。对57例静脉源性营养性溃疡患者进行了生活质量研究。第一组30例患者接受标准治疗,第二组27例患者接受标准治疗并结合一个疗程的光动力治疗。采用EuroQol-5D-5L调查系统和EQ-VAS视觉模拟量表对两组患者的生活质量进行问卷调查。分别于治疗开始时、治疗开始后10天和治疗开始后6周进行生活质量评估。结果表明,两组患者的生活质量均有显著改善,但第2组患者的生活质量改善程度高出20.7%。对生活质量改善的动态分析显示,治疗开始后10天,第一组患者的平均生活质量指标提高了26.7%,第二组提高了43%,6周后,第一组患者的平均生活质量指标提高了32.7%,第二组提高了53.4%。结论。使用光动力疗法治疗静脉营养性溃疡显著影响患者的生活质量,与第一组患者相比,表现在抗炎作用和短期疼痛综合征减轻(减少76.2%)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Improvement the quality of life of patients with trophic ulcers of venous etiology in the application of photodynamic therapy
Purpose. To analyze quality of life dynamics of patients with trophic venous ulcers of the lower limbs after the treatment with the use of photodynamic therapy. Materials and methods. Quality of life research was conducted in 57 patients with trophic ulcers of venous etiology. The first group included 30 patients who received standard treatment, the second group — 27 patients, in which standard treatment was combined with a course of photodynamic therapy. To assess the quality of life of the patients in both groups, a questionnaire was conducted using the EuroQol-5D-5L survey system and the visual analogue scale EQ-VAS. The quality of life assessment was carried out at the beginning of treatment, 10 days and 6 weeks after starting treatment. Results. The results indicate a significant improvement in the quality of life in both groups, but the degree of improvement in this indicator in group 2 was 20.7 % higher.An analysis of the dynamics of improvement in quality of life showed an increase in the mean of the indicator 10 days after the beginning of treatment in patients in the first group of 26.7 %, the second group by 43 %, and in 6 weeks, its increase was achieved in patients in the first group by 32.7 %, in the second group — by 53.4 %. Conclusions. The use of photodynamic therapy in the treatment of venous trophic ulcers significantly affects the quality of life, which is manifested in the anti-inflammatory effect and reduction of pain syndrome in the shorter term (by 76.2 %), compared with patients in the first group.
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