细胞外囊泡是多发性硬化的可靠生物标志物吗?

C. Avolio
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摘要

在过去的几十年里,越来越多的人关注细胞外囊泡(EVs)作为一种新的特化结构,由细胞释放,用于细胞间的通讯,而不是直接的细胞接触。EVs是一种小的膜囊泡,通常分为微囊泡(MVs)(直径100-1000nm)和外泌体(EXOs)(直径40-100nm),它们在大小、含量和形成机制上有所不同[1]。它们参与不同的生物过程,包括神经炎症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Are Extracellular Vesicles Reliable Biomarkers in Multiple Sclerosis?
During the last decades growing attention has been given to extracellular vesicles (EVs) released by the cells as new specialized structures for intercellular communication without direct cell contact. EVs are small membrane vesicles, commonly distinguished in microvesicles (MVs) (100-1000nm in diameter) and exosomes (EXOs) (40-100nm in diameter), which differ in size, content and mechanism of formation [1]. They are involved in different biological processes, including neuroinflammation.
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