遗传和其他生物标志物在非小细胞肺癌预后中的作用

D. Schveigert, S. Cicėnas, Jaroslav Bublevič, Renatas Aškinis, V. Šapoka, J. Didziapetriene
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引用次数: 2

摘要

非小细胞肺癌(NSCLC)的发展是一个多步骤的过程,由多种因素触发和维持。非小细胞肺癌发生的许多步骤、危险因素和生物标志物已被确定;然而,目前还没有为这些患者建立一致的个性化医疗模式。不同的各种基因表达、突变基因的产物以及循环核酸或肿瘤细胞等其他标记物已被证明是非小细胞肺癌的潜在生物标志物,也是新的治疗策略的潜在靶点。本文将重点介绍在非小细胞肺癌预后中有前景的生物标志物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The role of genetic and other biomarkers in NSCLC prognosis
The development of non-small-cell lung cancer (NSCLC) is a multistep process, which is triggered and maintained by various factors. Many steps of non-small-cell lung carcinogenesis, risk factors and biomarkers have been identified; however no consistent model has been established of personalized medicine for these patients. Distinct various gene expression, products of mutated genes and other markers such as circulating nucleic acids or tumor cells has been proven to be potential biomarkers of non-small cell lung cancer as well as potential targets for new treatment strategies. This article will highlight promising biomarkers in non-small cell lung cancer prognosis.
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来源期刊
Central European Journal of Medicine
Central European Journal of Medicine 医学-医学:内科
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4-8 weeks
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